种族、职业与肺癌：利用死亡证明数据检测差异
Race, occupation, and lung cancer: detecting disparities with death certificate data.
作者信息
Birdsey Jan, Alterman Toni, Petersen Martin R
机构信息
Division of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, Cincinnati, OH 45226, USA.
出版信息
J Occup Environ Med. 2007 Nov;49(11):1257-63. doi: 10.1097/JOM.0b013e318154c094.
OBJECTIVES
To determine whether the analysis of death certificate data would reveal the same relationship among race, occupational exposure, and lung cancer mortality observed by a large cohort study.
METHODS
An occupation-specific mortality odds ratio (MOR) for lung cancer (ICD-162) versus all other causes was calculated for 218,341 black men and white men who had been employed in the metal industries.
RESULTS
Black men were at increased risk for lung cancer mortality when compared with white men among the 4668 oven workers (MOR = 1.38, 95% CI = 1.10 to 1.73), but not among the 33,605 white-collar workers (MOR = 0.95, 95% CI = 0.74 to 1.23).
CONCLUSIONS
Our findings corroborate a previously demonstrated association among exposure to carcinogenic coke oven emissions, race, and lung cancer mortality, and support the use of death certificate data to help identify occupations with racial disparities in lung cancer mortality.
目的
确定对死亡证明数据的分析是否会揭示在一项大型队列研究中所观察到的种族、职业暴露与肺癌死亡率之间的相同关系。
方法
计算了218,341名曾在金属行业工作的黑人和白人男性中，肺癌（国际疾病分类代码162）相对于所有其他死因的特定职业死亡率比值比（MOR）。
结果
在4668名烤炉工人中，黑人男性的肺癌死亡风险高于白人男性（MOR = 1.38，95%置信区间 = 1.10至1.73），但在33,605名白领工人中并非如此（MOR = 0.95，95%置信区间 = 0.74至1.23）。
结论
我们的研究结果证实了先前已证明的致癌焦炉排放暴露、种族与肺癌死亡率之间的关联，并支持使用死亡证明数据来帮助识别肺癌死亡率存在种族差异的职业。
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