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[肺结核与艾滋病。54例患者的研究]

[Tuberculosis and AIDS. Study of 54 patients].

作者信息

Aguirrebengoa L, Montejo M, Urkijo J C, Urra E, Gutiérrez A, Mendoza F, Zalacaín R, González de Zárate P, Aguirre C

机构信息

Cátedra de Patología Médica, Universidad del País Vasco.

出版信息

Enferm Infecc Microbiol Clin. 1991 Aug-Sep;9(7):399-404.

PMID:1799608
Abstract

We present 54 cases of tuberculosis (TBC) and Acquired Immunodeficiency Syndrome (AIDS) that were observed during five years and represent 37% of our AIDS patients. TBC was diagnosed before AIDS in 7, after AIDS in 5 and simultaneously in 42. Eighty-seven per cent were intravenous drug users (IVDU) and no hemophilia cases were recorded. The tuberculin skin test (PPD) showed a reaction greater than 5 mm in 43%. Prophylaxis has not been used in any patient. TBC was localized in 39% and disseminated in 61%; the lung was the main organ involved. Diagnosis was established by culture in 42 cases and by pathology exam in 12 cases. Eighteen patients had multiple isolations, while 36 had a single one. Co-occurrence with other opportunistic infections was observed in 27 cases. Death related to TBC was seen in 3 patients, and there were no differences in survival between disseminated and localized presentations. Compliance of treatment was very low and follow-up was not achieved in large number of patients.

摘要

我们呈现了54例在五年间观察到的结核病(TBC)与获得性免疫缺陷综合征(AIDS)病例,占我们AIDS患者的37%。7例TBC在AIDS之前被诊断出来,5例在AIDS之后,42例同时被诊断。87%为静脉注射吸毒者(IVDU),未记录到血友病病例。结核菌素皮肤试验(PPD)显示43%的患者反应大于5毫米。所有患者均未使用预防措施。TBC局限型占39%,播散型占61%;肺部是主要受累器官。42例通过培养确诊,12例通过病理检查确诊。18例患者有多次分离培养结果,36例为单次结果。27例观察到与其他机会性感染同时存在。3例患者死于TBC,播散型和局限型在生存率上无差异。治疗依从性非常低,大量患者未完成随访。

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