Cadarette Suzanne M, Beaton Dorcas E, Gignac Monique A M, Jaglal Susan B, Dickson Leigh, Hawker Gillian A
Osteoporosis Research Program, Women's College Hospital, Toronto, Ontario, Canada.
J Clin Epidemiol. 2007 Dec;60(12):1306-11. doi: 10.1016/j.jclinepi.2007.02.010. Epub 2007 Jun 28.
To examine the validity of both self-report of having had dual-energy x-ray absorptiometry (DXA) and self-reported DXA test results.
Participants were recruited in 2003 and 2004 from a population-based study of women aged 65-90 years examining osteoporosis management in Ontario, Canada (N=871). Women reporting having had a DXA were eligible and asked to report the results of their most recent test. Participant responses were compared against DXA reports obtained from physicians.
We obtained 413 (81%) physician records among the 510 women who reported having had a DXA test. Of these, the positive predictive value for self-report of having had a DXA was 93%. The weighted kappa statistic for the agreement between self-report and actual DXA results was 0.42 (95% confidence interval=0.34-0.49). Although 84% of those with normal bone reported this, only 29% of those with osteopenia and 62% with osteoporosis reported their results correctly. Self-report of a clinical diagnosis of osteoporosis was better among those with a low trauma fracture, yet underestimated osteoporosis prevalence by 24%.
There is minimal measurement error in self-report of having had a DXA test. Self-report of DXA results will underestimate osteoporosis prevalence and is not a good proxy for clinical diagnosis.
检验双能X线吸收法（DXA）检查的自我报告及自我报告的DXA检测结果的有效性。
2003年和2004年从一项基于人群的加拿大安大略省65至90岁女性骨质疏松管理研究中招募参与者（N = 871）。报告接受过DXA检查的女性符合条件，并被要求报告其最近一次检查的结果。将参与者的回答与从医生处获得的DXA报告进行比较。
在报告接受过DXA检查的510名女性中，我们获得了413份（81%）医生记录。其中，DXA检查自我报告的阳性预测值为93%。自我报告与实际DXA结果一致性的加权kappa统计量为0.42（95%置信区间 = 0.34 - 0.49）。虽然84%骨量正常的人报告了这一情况，但骨量减少者中只有29%、骨质疏松者中只有62%正确报告了他们的结果。低创伤性骨折患者中骨质疏松临床诊断的自我报告情况较好，但仍将骨质疏松患病率低估了24%。
DXA检查自我报告中的测量误差极小。DXA结果的自我报告将低估骨质疏松患病率，且不是临床诊断的良好替代指标。
