Evers A W M, Duller P, van de Kerkhof P C M, van der Valk P G M, de Jong E M G J, Gerritsen M J P, Otero E, Verhoeven E W M, Verhaak C M, Kraaimaat F W
Departments of Medical Psychology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
Br J Dermatol. 2008 Jan;158(1):101-8. doi: 10.1111/j.1365-2133.2007.08296.x. Epub 2007 Nov 10.
In dermatological research and clinical practice, there is a need for comprehensive self-report instruments that assess a broad spectrum of health implications of chronic skin diseases, including generic and skin-specific aspects of disease-related quality of life. The advantages of dermatology-specific, multidimensional instruments over generic instruments or single-dimensional quality-of-life measures are in the detailed and specific information they provide about health areas that are affected by the skin condition and that may change through therapeutic intervention.
The development of a multidimensional health status inventory for chronic skin diseases (Impact of Chronic Skin Disease on Daily Life, ISDL) is described. The dermatology-specific part of the inventory assesses dimensions of physical functioning, more specifically skin status, physical symptoms of itch, pain and fatigue and scratching responses as well as disease-related stressors like stigmatization. The generic part gauges dimensions of psychological functioning, disease-related impact, illness cognitions and social support by means of existing scales validated for other chronic diseases.
Reliability and validity of the questionnaire were studied in various samples of patients with psoriasis and atopic dermatitis.
The ISDL showed high reliability and test-retest reliability in both patient groups. Convergent validity was indicated by moderate to strong correlations with other validated questionnaires. The scales proved sensitive to change both for dermatological ultraviolet B radiation therapy and cognitive behavioural treatment for itching.
With its convincing results for reliability and validity the present evaluation supports the usefulness and applicability of the instrument for different chronic skin diseases.
在皮肤病学研究和临床实践中，需要有全面的自我报告工具来评估慢性皮肤病对健康的广泛影响，包括疾病相关生活质量的一般方面和皮肤特定方面。皮肤病专用的多维工具相对于一般工具或单维生活质量测量方法的优势在于，它们能提供关于受皮肤状况影响且可能通过治疗干预而改变的健康领域的详细具体信息。
描述一种用于慢性皮肤病的多维健康状况量表（慢性皮肤病对日常生活的影响，ISDL）的开发。该量表的皮肤病专用部分评估身体功能维度，更具体地说是皮肤状况、瘙痒、疼痛和疲劳的身体症状以及搔抓反应，还有诸如污名化等与疾病相关的应激源。一般部分通过针对其他慢性疾病验证过的现有量表来衡量心理功能、疾病相关影响、疾病认知和社会支持等维度。
在银屑病和特应性皮炎患者的不同样本中研究该问卷的信度和效度。
ISDL在两组患者中均显示出高信度和重测信度。与其他已验证问卷的中度至强相关性表明了收敛效度。这些量表对皮肤病紫外线B辐射治疗和瘙痒的认知行为治疗的变化均证明敏感。
鉴于其在信度和效度方面令人信服的结果，本评估支持该工具对不同慢性皮肤病的实用性和适用性。
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