Evers A W M, Lu Y, Duller P, van der Valk P G M, Kraaimaat F W, van de Kerkhof P C M
Department of Medical Psychology, Radboud University Nijmegen Medical Center, 6500 HB Nijmegen, The Netherlands.
Br J Dermatol. 2005 Jun;152(6):1275-81. doi: 10.1111/j.1365-2133.2005.06565.x.
Chronic skin diseases, such as atopic dermatitis and psoriasis, are known to affect quality of life by heightening psychological distress. Knowledge about factors contributing to psychological distress is essential for supporting physicians in diagnostic and multidisciplinary treatment options for patients psychologically at risk.
To examine whether generic physical, psychological and social factors relevant to patients with chronic diseases might contribute to psychological distress in adults with psoriasis and atopic dermatitis.
Self-report data on clinical skin status, physical symptoms of itching and fatigue, impact of the disease on daily life, illness cognitions and social support were collected from 128 patients with psoriasis and 120 patients with atopic dermatitis (aged over 16 years).
For patients with either skin disease, clinical status and physical symptoms of itching scarcely affected psychological distress. Instead, higher levels of fatigue, perceived helplessness and less social support best predicted psychological distress in patients with both skin diseases in multiple regression analyses.
Results demonstrate that generic physical, psychological and social aspects play a role in chronic skin diseases and suggest that multidisciplinary care for patients with psoriasis and atopic dermatitis can be greatly improved by integrating common screening and treatment components for chronic diseases.
已知慢性皮肤病，如特应性皮炎和银屑病，会通过加剧心理困扰来影响生活质量。了解导致心理困扰的因素对于帮助医生为有心理风险的患者选择诊断和多学科治疗方案至关重要。
研究与慢性病患者相关的一般身体、心理和社会因素是否会导致银屑病和特应性皮炎成人患者出现心理困扰。
收集了128例银屑病患者和120例特应性皮炎患者（年龄超过16岁）关于临床皮肤状况、瘙痒和疲劳的身体症状、疾病对日常生活的影响、疾病认知和社会支持的自我报告数据。
对于这两种皮肤病患者，临床状况和瘙痒的身体症状几乎不会影响心理困扰。相反，在多元回归分析中，更高程度的疲劳、感知到的无助感以及更少的社会支持最能预测这两种皮肤病患者的心理困扰。
结果表明，一般身体、心理和社会方面在慢性皮肤病中发挥作用，并表明通过整合慢性病的常见筛查和治疗要素，可大大改善对银屑病和特应性皮炎患者的多学科护理。
