[血友病性关节病。血友病临床表现中的治疗方法]

[Hemophilic arthropathy. The therapeutic approaches in the clinical picture of hemophilia].

作者信息

Ambriz-Fernández R, Rodríguez-Moyado H, Villanueva R M, Muñoz-Olvera R, Gacitua-Zambrano S

机构信息

Banco Central de Sangre, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social.

出版信息

Gac Med Mex. 1991 May-Jun;127(3):233-9; discussion 239-40.

PMID:1800217

Abstract

The ambulatory treatment of hemophilic arthropathy decreased the amount of replacement therapy with factor VIII from 3,220,000 U in 1984 to 2,217,700 U (32%) in 1988. Radioactive synovectomy diminished the number of hemarthroses in 97 per cent. Intraarticular dexamethasone reduced bleeding episodes and improved joint function in 48 per cent. These procedures for hemophilic arthropathy allowed to integrate the patient into society and diminished transfusion risks.

摘要

血友病性关节病的门诊治疗使VIII因子替代疗法的用量从1984年的320万单位降至1988年的221.77万单位（减少了32%）。放射性滑膜切除术使97%的关节积血次数减少。关节内注射地塞米松使48%的患者出血发作次数减少，关节功能得到改善。这些针对血友病性关节病的治疗方法使患者能够融入社会，并降低了输血风险。