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恙虫病东方体直接侵袭所致急性肾小管坏死引起的急性肾衰竭

Acute renal failure due to acute tubular necrosis caused by direct invasion of Orientia tsutsugamushi.

作者信息

Kim Dong-Min, Kang Dae Woong, Kim Jong O, Chung Jong Hoon, Kim Hyun Lee, Park Chi Young, Lim Sung-Chul

机构信息

Department of Internal Medicine, Chosun University College of Medicine, 588 Seosuk-dong, Dong-gu, Gwangju 501-717, South Korea.

出版信息

J Clin Microbiol. 2008 Apr;46(4):1548-50. doi: 10.1128/JCM.01040-07. Epub 2007 Nov 14.

DOI:10.1128/JCM.01040-07
PMID:18003808
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2292935/
Abstract

We describe a scrub typhus patient with acute renal failure for whom a diagnosis was made based on serology as well as immunohistochemical (IHC) staining and an electron microscopic examination (EM) of a renal biopsy specimen. For our case, we demonstrated by IHC staining and EM that renal failure was caused by acute tubular necrosis due to a direct invasion of Orientia tsutsugamushi.

摘要

我们描述了一名患有急性肾衰竭的恙虫病患者，其诊断基于血清学、免疫组织化学（IHC）染色以及对肾活检标本的电子显微镜检查（EM）。对于我们的病例，我们通过IHC染色和EM证明，肾衰竭是由恙虫病东方体的直接侵袭导致急性肾小管坏死引起的。

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Severe scrub typhus confirmed early via immunohistochemical staining.通过免疫组织化学染色早期确诊为重症恙虫病。
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Usefulness of eschar PCR for diagnosis of scrub typhus.焦痂聚合酶链反应在恙虫病诊断中的应用价值
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A case of acute renal failure, rhabdomyolysis and disseminated intravascular coagulation associated with scrub typhus.一例与恙虫病相关的急性肾衰竭、横纹肌溶解症和弥散性血管内凝血病例。
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