Kraff O, Theysohn J M, Maderwald S, Saylor C, Ladd S C, Ladd M E, Barkhausen J
Erwin L. Hahn Institute for Magnetic Resonance Imaging, Universität Duisburg-Essen, Essen.
Rofo. 2007 Dec;179(12):1231-5. doi: 10.1055/s-2007-963607. Epub 2007 Nov 14.
Measurement protocols which have been optimized for MRI at field strengths of 1.5 T or 3 T cannot be directly transferred to 7 T. Specific absorption rate limitations, different tissue relaxation times, as well as new image artifacts require adjustments of the sequence parameters. The goal of our study was to investigate and optimize various sequences for 7 T imaging of the knee.
Starting with sequences used on a standard 1.5 T scanner, the parameters were modified to obtain optimal image contrast, maximum coverage, and the highest spatial resolution within a reasonable acquisition time. All sequences were optimized in two healthy volunteers and then tested in 10 patients with various pathologies. High-resolution 7 T images with several SE and GRE sequences were acquired and compared to 1.5 T images.
A comparison of 1.5 T and 7 T images clearly shows the advantage of MRI at higher field strengths, especially the higher SNR which could be translated into higher spatial resolution. The MEDIC sequence appears to be very well suited for the assessment of cartilage pathologies at 7 T. Using the DESS sequence, full coverage of the knee can be obtained with a very high resolution of 0.4 x 0.4 x 1.0 mm(3) within 7 minutes. Despite optimization of the STIR sequence parameters, bone marrow edema is better visualized at 1.5 T compared to 7 T. The PD TSE renders excellent image quality at 7 T. The total acquisition time of the 7 T protocol is approximately 40 minutes.
Gradient echo sequences provide excellent image contrast at very high spatial resolution in a reasonable scan time. However, not all sequences used at 1.5 T are currently well suited for high-field imaging, in particular SAR-intensive sequences. Imaging of meniscal tears and lesions of the cruciate ligaments may benefit from the higher spatial resolution. The most favorable clinical indication for knee examinations at 7 T currently appears to be cartilage imaging.
针对1.5 T或3 T场强优化的MRI测量协议不能直接应用于7 T。特定吸收率限制、不同的组织弛豫时间以及新的图像伪影都需要调整序列参数。我们研究的目的是针对膝关节的7 T成像研究并优化各种序列。
从标准1.5 T扫描仪上使用的序列开始,修改参数以在合理的采集时间内获得最佳图像对比度、最大覆盖范围和最高空间分辨率。所有序列在两名健康志愿者身上进行了优化,然后在10名患有各种病变的患者身上进行了测试。采集了多个SE和GRE序列的高分辨率7 T图像,并与1.5 T图像进行了比较。
1.5 T和7 T图像的比较清楚地显示了高场强MRI的优势,尤其是更高的SNR,这可以转化为更高的空间分辨率。MEDIC序列似乎非常适合在7 T下评估软骨病变。使用DESS序列,在7分钟内可以以0.4×0.4×1.0 mm³的非常高分辨率获得膝关节的全层覆盖。尽管优化了STIR序列参数,但与7 T相比,1.5 T下骨髓水肿的显示效果更好。PD TSE在7 T下提供了出色的图像质量。7 T协议的总采集时间约为40分钟。
梯度回波序列在合理的扫描时间内以非常高的空间分辨率提供了出色的图像对比度。然而,并非所有在1.5 T下使用的序列目前都适合高场成像,特别是SAR密集型序列。半月板撕裂和交叉韧带损伤的成像可能受益于更高的空间分辨率。目前7 T膝关节检查最有利的临床适应症似乎是软骨成像。