人体之窗——活体高场磁共振研究及其在医学和心理学中的应用。

MR Center of Excellence, Medical University of Vienna, Lazarettgasse 14, A-1090 Vienna, Austria.

Sensors (Basel). 2010;10(6):5724-57. doi: 10.3390/s100605724. Epub 2010 Jun 8.

Analogous to the evolution of biological sensor-systems, the progress in "medical sensor-systems", i.e., diagnostic procedures, is paradigmatically described. Outstanding highlights of this progress are magnetic resonance imaging (MRI) and spectroscopy (MRS), which enable non-invasive, in vivo acquisition of morphological, functional, and metabolic information from the human body with unsurpassed quality. Recent achievements in high and ultra-high field MR (at 3 and 7 Tesla) are described, and representative research applications in Medicine and Psychology in Austria are discussed. Finally, an overview of current and prospective research in multi-modal imaging, potential clinical applications, as well as current limitations and challenges is given.

类似于生物传感器系统的发展，“医学传感器系统”，即诊断程序，也在范式上得到了描述。这方面进展的突出亮点是磁共振成像（MRI）和光谱学（MRS），它们能够以无与伦比的质量从人体中无创、活体获取形态、功能和代谢信息。本文描述了高场和超高场磁共振（3 和 7 特斯拉）的最新进展，并讨论了奥地利在医学和心理学领域的代表性研究应用。最后，本文概述了多模态成像的当前和未来研究、潜在的临床应用以及当前的局限性和挑战。