Seifert Christian L, Woeller Andreas, Valet Michael, Zimmer Claus, Berthele Achim, Tölle Thomas, Sprenger Till
Technische Universitaet Muenchen-Neurologische Klinik, Munich, Germany.
Headache. 2008 Mar;48(3):448-52. doi: 10.1111/j.1526-4610.2007.00965.x. Epub 2007 Nov 13.
Pineal cysts have been suggested to be linked to headache pathogenesis. However, no systematic studies on this topic have been performed so far.
The aim of this study was to investigate the relationship between pineal cysts and headache and to determine the relevance of the cyst size in this context.
We conducted a case-control study of patients who consulted the neurological department between 1999 and 2006 to investigate the relationship between pineal cysts and headache and to determine the relevance of the cyst size.
A total of 51 patients with pineal cyst were identified, thereby 51% were suffering from headache (half of them had migraine), whereas in the control group, only 25% had headache (thereof 31% suffered from migraine). There was a significant relationship between headache (as well as migraine) and pineal cysts (chi-square test), but no significant difference in pineal cyst diameter between the patient group with headache versus without headache (t-test).
Our data provide evidence for a causal relationship between pineal cysts and headache, respectively, migraine in this patient cohort.
松果体囊肿被认为与头痛的发病机制有关。然而，迄今为止尚未针对该主题进行系统研究。
本研究旨在探讨松果体囊肿与头痛之间的关系，并确定囊肿大小在此背景下的相关性。
我们对1999年至2006年间到神经科就诊的患者进行了一项病例对照研究，以调查松果体囊肿与头痛之间的关系，并确定囊肿大小的相关性。
共识别出51例松果体囊肿患者，其中51%患有头痛（其中一半患有偏头痛），而在对照组中，只有25%患有头痛（其中31%患有偏头痛）。头痛（以及偏头痛）与松果体囊肿之间存在显著关系（卡方检验），但有头痛与无头痛的患者组之间松果体囊肿直径无显著差异（t检验）。
我们的数据为该患者队列中松果体囊肿与头痛及偏头痛之间的因果关系提供了证据。
