斑块型汗管瘤：两例误诊为微囊性附属器癌的病例。
Plaque-type syringoma: two cases misdiagnosed as microcystic adnexal carcinoma.
作者信息
Suwattee Pitiporn, McClelland Matthew C, Huiras Erin E, Warshaw Erin M, Lee Peter K, Kaye Valda N, McCalmont Timothy H, Niehans Gloria A
机构信息
Department of Dermatology, University of Minnesota, Minneapolis, MN 55417, USA.
出版信息
J Cutan Pathol. 2008 Jun;35(6):570-4. doi: 10.1111/j.1600-0560.2007.00843.x. Epub 2007 Nov 12.
BACKGROUND
Plaque-type syringoma is a rare variant of syringoma. This benign neoplasm may be easily misdiagnosed as microcystic adnexal carcinoma (MAC), potentially resulting in unnecessary surgery with disfiguring consequences.
METHODS
We report two cases of plaque-type syringoma that were initially diagnosed as MAC. Microscopically, these lesions were composed of nests of cuboidal cells arrayed within sclerotic collagen in the upper dermis. The deep reticular dermis was spared. No perineural involvement was observed.
RESULTS AND CONCLUSIONS
Our cases are discussed in the context of histopathologic diagnosis. Detailed histopathologic findings of syringoma, as well as other considerations in the differential diagnosis, are reviewed. We also include a review of all cases of plaque-type syringoma published to date.
背景
斑块型汗管瘤是汗管瘤的一种罕见变异型。这种良性肿瘤可能很容易被误诊为微囊性附属器癌（MAC），可能导致不必要的手术，造成毁容后果。
方法
我们报告两例最初被诊断为MAC的斑块型汗管瘤病例。显微镜下，这些病变由排列在上层真皮硬化胶原内的立方体细胞巢组成。深层网状真皮未受累。未观察到神经周围侵犯。
结果与结论
我们的病例在组织病理学诊断的背景下进行了讨论。回顾了汗管瘤的详细组织病理学发现以及鉴别诊断中的其他考虑因素。我们还对迄今为止发表的所有斑块型汗管瘤病例进行了综述。
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