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自终止氧化自由基环化反应

Self-terminating, oxidative radical cyclizations.

作者信息

Dreessen Tim, Jargstorff Christian, Lietzau Lars, Plath Christian, Stademann Arne, Wille Uta

机构信息

Institut für Organische Chemie, Universität Kiel, Olshausenstr, 40, 24098 Kiel, Germany.

出版信息

Molecules. 2004 May 31;9(6):480-97. doi: 10.3390/90600480.

DOI:10.3390/90600480
PMID:18007448
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6147322/
Abstract

The recently discovered novel concept of self-terminating, oxidative radical cyclizations, through which alkynes can be converted into carbonyl compounds under very mild reaction conditions using O-centered inorganic and organic radicals as oxidants, is described.

摘要

本文描述了最近发现的一种新颖的自终止氧化自由基环化概念,通过该概念,炔烃在非常温和的反应条件下,以氧中心的无机和有机自由基作为氧化剂,可以转化为羰基化合物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e3/6147322/42094c38eb5b/molecules-09-00480-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e3/6147322/83b3c5b8c98c/molecules-09-00480-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e3/6147322/cd4a82aa08bd/molecules-09-00480-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e3/6147322/b34c205ae8df/molecules-09-00480-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e3/6147322/378607ce20e5/molecules-09-00480-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e3/6147322/bf900769023f/molecules-09-00480-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e3/6147322/a1c2113d2f57/molecules-09-00480-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e3/6147322/735d1cde4d42/molecules-09-00480-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e3/6147322/9d40f4db69e1/molecules-09-00480-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e3/6147322/42094c38eb5b/molecules-09-00480-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e3/6147322/83b3c5b8c98c/molecules-09-00480-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e3/6147322/cd4a82aa08bd/molecules-09-00480-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e3/6147322/b34c205ae8df/molecules-09-00480-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e3/6147322/378607ce20e5/molecules-09-00480-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e3/6147322/bf900769023f/molecules-09-00480-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e3/6147322/a1c2113d2f57/molecules-09-00480-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e3/6147322/735d1cde4d42/molecules-09-00480-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e3/6147322/9d40f4db69e1/molecules-09-00480-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e3/6147322/42094c38eb5b/molecules-09-00480-g009.jpg

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本文引用的文献

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Flight from the Tyranny of Tin: The Quest for Practical Radical Sources Free from Metal Encumbrances.逃离锡的束缚:探寻摆脱金属阻碍的实用激进来源。
Angew Chem Int Ed Engl. 1998 Dec 4;37(22):3072-3082. doi: 10.1002/(SICI)1521-3773(19981204)37:22<3072::AID-ANIE3072>3.0.CO;2-9.
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A warning on the use of radical traps as a test for radical mechanisms: they react with palladium hydrido complexes.
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Photochemistry of N-isopropoxy-substituted 2(1H)-pyridone and 4-p-tolylthiazole-2(3H)-thione: alkoxyl-radical release (spin-trapping, EPR, and transient spectroscopy) and its significance in the photooxidative induction of DNA strand breaks.
J Org Chem. 2002 Aug 23;67(17):6041-9. doi: 10.1021/jo025856w.
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Self-terminating, oxidative radical cyclizations: a novel reaction of acyloxyl radicals.自终止氧化自由基环化反应:酰氧基自由基的一种新反应
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A New Synthesis of Alkyl Nitrites: The Reaction of Alkyl Alcohols with Nitric Oxide in Organic Solvents.亚硝酸烷基酯的新合成方法:烷基醇与一氧化氮在有机溶剂中的反应。
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