Donnenfeld E D, Perry H D, Gibralter R P, Ingraham H J, Udell I J
Department of Ophthalmology, North Shore University Hospital, Manhasset, NY.
Ophthalmology. 1991 Nov;98(11):1674-8. doi: 10.1016/s0161-6420(91)32070-0.
Floppy eyelid syndrome is a recently described entity, which characteristically involves overweight individuals. The characteristic findings are an upper lid that may be readily everted, tarsal laxity, and diffuse papillary conjunctival changes. The cause of floppy eyelid syndrome is believed to be a mechanical disorder due to the eversion of the lids while sleeping. The cause of keratoconus remains uncertain. There are strong proponents to a mechanical etiology for this disease. The authors report five cases of floppy eyelid syndrome with concomitant keratoconus. One patient with bilateral keratoconus had bilateral symmetric floppy eyelid syndrome. The other four patients had asymmetric keratoconus and floppy eyelid syndrome. In all four patients, the keratoconus was significantly worse in the eye with the more severe case of floppy eyelid syndrome. In addition, these four patients all gave a history of sleeping with their head facing predominantly on the side with the floppy eyelid syndrome and keratoconus. Two patients with keratoconus and floppy eyelid syndrome were able to undergo successful contact lens rehabilitation of their keratoconus after treatment of the floppy eyelid syndrome.
眼睑松弛综合征是一种最近才被描述的病症，其特征性地累及超重个体。特征性表现为上睑易于外翻、睑板松弛以及弥漫性乳头样结膜改变。眼睑松弛综合征的病因被认为是睡眠时眼睑外翻导致的一种机械性紊乱。圆锥角膜的病因仍不确定。有很多人支持该病的机械性病因学说。作者报告了5例伴有圆锥角膜的眼睑松弛综合征病例。1例双侧圆锥角膜患者患有双侧对称性眼睑松弛综合征。其他4例患者患有不对称性圆锥角膜和眼睑松弛综合征。在所有4例患者中，圆锥角膜在眼睑松弛综合征病情更严重的一侧眼睛中明显更严重。此外，这4例患者均有睡觉时头部主要朝向患有眼睑松弛综合征和圆锥角膜一侧的病史。2例患有圆锥角膜和眼睑松弛综合征的患者在眼睑松弛综合征得到治疗后，其圆锥角膜成功接受了隐形眼镜矫正。
