Cuadrado M L, Young W B, Fernández-de-las-Peñas C, Arias J A, Pareja J A
Department of Neurology, Fundación Hospital Alcorcón and Rey Juan Carlos University, Alcorcón, Madrid, Spain.
Cephalalgia. 2008 Jan;28(1):87-91. doi: 10.1111/j.1468-2982.2007.01485.x. Epub 2007 Nov 16.
Cephalic and extracephalic allodynia are recognized as a common sign of sensory sensitization during migraine episodes. However, the occurrence of body pain in migraine has not been thoroughly explored. Here we report three patients presenting with spontaneous body pain in association with migraine attacks. A 41-year-old woman experienced face and limb pain along with migraine headaches; it started before, during or after headache, was usually ipsilateral to head pain, and could last from minutes to days. A 39-year-old woman had pain in her right limbs, back and neck for 30-60 min prior to right-sided migraine headaches. A 30-year-old woman perceived pain in her left upper limb for 24-48 h prior to left-sided migraine headaches. All patients had allodynia to mechanical stimuli over the painful areas. Spontaneous body pain may be associated with migraine attacks. Together with allodynia, this might be a consequence of central sensitization.
头面部和头外部位的痛觉过敏被认为是偏头痛发作期间感觉敏化的常见体征。然而，偏头痛中身体疼痛的发生情况尚未得到充分研究。在此，我们报告3例伴有偏头痛发作的自发性身体疼痛患者。一名41岁女性在偏头痛发作时伴有面部和肢体疼痛；疼痛在头痛之前、期间或之后开始，通常与头痛同侧，可持续数分钟至数天。一名39岁女性在右侧偏头痛发作前30 - 60分钟，右侧肢体、背部和颈部出现疼痛。一名30岁女性在左侧偏头痛发作前24 - 48小时，左侧上肢出现疼痛。所有患者在疼痛区域对机械刺激均有痛觉过敏。自发性身体疼痛可能与偏头痛发作有关。连同痛觉过敏一起，这可能是中枢敏化的结果。
