没有证据表明单胺氧化酶A（MAOA）与童年逆境在反社会行为方面存在相互作用。
No evidence for interaction between MAOA and childhood adversity for antisocial behavior.
作者信息
Prichard Zoë, Mackinnon Andrew, Jorm Anthony F, Easteal Simon
机构信息
Predictive Medicine Group, John Curtin School of Medical Research, Australian National University, Canberra, Australia.
出版信息
Am J Med Genet B Neuropsychiatr Genet. 2008 Mar 5;147B(2):228-32. doi: 10.1002/ajmg.b.30581.
Previous reports have identified an interaction between an MAOA promoter polymorphism and childhood adversity for antisocial behavioral outcomes in males. This study attempted to replicate this finding in an Australian community survey of 1,002 Caucasian men aged 20-24 years. Greater childhood adversity was associated with later antisocial behavior, but no association was observed between MAOA genotype and antisocial behavior, and no interaction was found between childhood adversity and MAOA genotype for antisocial behavior. This study does not support previous reports of an interaction between MAOA genotype and childhood adversity for antisocial behavior in males.
先前的报告已确定，单胺氧化酶A（MAOA）启动子多态性与童年逆境之间的相互作用会影响男性的反社会行为结果。本研究试图在一项针对1002名年龄在20至24岁之间的澳大利亚白人男性的社区调查中重现这一发现。童年逆境程度越高，日后出现反社会行为的可能性越大，但未观察到MAOA基因型与反社会行为之间存在关联，也未发现童年逆境与MAOA基因型在反社会行为方面存在相互作用。本研究不支持先前关于MAOA基因型与童年逆境在男性反社会行为方面存在相互作用的报告。
Zotero 插件