Zhao Bao, Cao Yanmiao, Zhang Liang, Zhang Wenxin
Department of Psychology, Shandong Normal University, Jinan, China.
Front Psychol. 2020 Feb 18;11:60. doi: 10.3389/fpsyg.2020.00060. eCollection 2020.
Effortful control (EC) plays a crucial role in psychopathology disorders. Emerging studies have paid attention to the effects of G × E interaction on EC. The present study investigated interactions between monoamine oxidase A () T941G polymorphism with parenting practices on EC in a sample of 1,531 Chinese adolescents. The adolescents completed the Early Adolescent Temperament Questionnaire-Revised (EATQ-R) EC scale and the Parenting Style Index provided during the study to assess EC and parenting practices, respectively. T941G polymorphism exerted no effect on adolescent EC; however, results revealed that the gene interacted with parental acceptance/involvement in their associations with EC among boys. Specifically, although increased levels of parental acceptance/involvement benefited all adolescents, boys with G alleles of the gene exhibited higher sensitivity to parental acceptance/involvement, compared with T carriers; this interaction was not significant among girls. This study is the first to identify × parenting interaction on adolescent EC, further contributing to the literature in gene-EC.
努力控制（EC）在精神病理学障碍中起着至关重要的作用。新兴研究已经关注到基因与环境（G×E）相互作用对努力控制的影响。本研究在1531名中国青少年样本中，调查了单胺氧化酶A（MAOA）T941G多态性与养育方式对努力控制的相互作用。青少年分别完成了青少年早期气质问卷修订版（EATQ-R）努力控制量表和研究期间提供的养育方式指数，以评估努力控制和养育方式。MAOA T941G多态性对青少年努力控制没有影响；然而，结果显示，在男孩中，MAOA基因与父母的接纳/参与在与努力控制的关联中存在相互作用。具体而言，虽然父母接纳/参与程度的提高对所有青少年都有益，但与携带T等位基因者相比，携带MAOA基因G等位基因的男孩对父母的接纳/参与表现出更高的敏感性；这种相互作用在女孩中不显著。本研究首次确定了MAOA与养育方式对青少年努力控制的相互作用，进一步丰富了MAOA基因与努力控制方面的文献。
