Thompson Jan, Thompson James R
Division of Cardiovascular Services, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA.
J Emerg Med. 2010 Jan;38(1):18-21. doi: 10.1016/j.jemermed.2007.06.021. Epub 2007 Nov 19.
Adult Attention Deficit Disorder is increasingly diagnosed and treated. Psychostimulant medications, such as methylphenidate, are commonly prescribed for this condition, but the long-term safety of such medications in an adult population is unknown at present. Because these medications are closely related to amphetamines, it is expected that toxic side effects would be similar. We present the case of a 27-year-old man who suffered an acute myocardial infarction due to coronary vasospasm related to use of methylphenidate complicated by concomitant use of pseudoephedrine.
成人注意力缺陷障碍越来越多地得到诊断和治疗。精神刺激药物,如哌醋甲酯,常用于治疗这种疾病,但目前这类药物在成人中的长期安全性尚不清楚。由于这些药物与苯丙胺密切相关,预计其毒副作用会相似。我们报告一例27岁男性病例,该患者因使用哌醋甲酯并同时使用伪麻黄碱导致冠状动脉痉挛,进而引发急性心肌梗死。