含汞离子和银离子的DNA双螺旋结构的制备。

Preparation of DNA double helical structures containing both mercury and silver ions.

作者信息

Yanagida Koji, Hamochi Nagisa, Sasano Kenichi, Okamoto Itaru, Ono Akira

机构信息

Department of Chemistry, Graduate School of Science and Engineering, Tokyo Metropolitan University, 1-1 Minamiosawa, Hachioji, Tokyo 192-0397 Japan.

出版信息

Nucleic Acids Symp Ser (Oxf). 2007(51):179-80. doi: 10.1093/nass/nrm090.

DOI:10.1093/nass/nrm090

PMID:18029645

Abstract

DNA duplexes consisting of metal-mediated pyrimidine base pairs, T-Hg(II)-T and C-Ag(I)-C, were prepared by mixing short oligodeoxyribonucleotides (ODNs) in the presence of the metal ions. The metal ions were arrayed linearly in the prepared double helical structures. The choice of sequence controls the order of the metal ions.

摘要

由金属介导的嘧啶碱基对（T-Hg(II)-T和C-Ag(I)-C）组成的DNA双链体，是通过在金属离子存在的情况下混合短链寡脱氧核糖核苷酸（ODN）制备而成的。金属离子在制备的双螺旋结构中呈线性排列。序列的选择控制着金属离子的排列顺序。