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瓦里安aS500电子射野影像装置(EPID)图像质量与剂量的优化

Optimization of image quality and dose for Varian aS500 electronic portal imaging devices (EPIDs).

作者信息

McGarry C K, Grattan M W D, Cosgrove V P

机构信息

Northern Ireland Regional Medical Physics Agency, Radiotherapy Physics Department, Northern Ireland Cancer Centre, Belfast City Hospital, Lisburn Road, Belfast BT97AB, Northern Ireland, UK.

出版信息

Phys Med Biol. 2007 Dec 7;52(23):6865-77. doi: 10.1088/0031-9155/52/23/006. Epub 2007 Nov 8.

Abstract

This study was carried out to investigate whether the electronic portal imaging (EPI) acquisition process could be optimized, and as a result tolerance and action levels be set for the PIPSPro QC-3V phantom image quality assessment. The aim of the optimization process was to reduce the dose delivered to the patient while maintaining a clinically acceptable image quality. This is of interest when images are acquired in addition to the planned patient treatment, rather than images being acquired using the treatment field during a patient's treatment. A series of phantoms were used to assess image quality for different acquisition settings relative to the baseline values obtained following acceptance testing. Eight Varian aS500 EPID systems on four matched Varian 600C/D linacs and four matched Varian 2100C/D linacs were compared for consistency of performance and images were acquired at the four main orthogonal gantry angles. Images were acquired using a 6 MV beam operating at 100 MU min(-1) and the low-dose acquisition mode. Doses used in the comparison were measured using a Farmer ionization chamber placed at d(max) in solid water. The results demonstrated that the number of reset frames did not have any influence on the image contrast, but the number of frame averages did. The expected increase in noise with corresponding decrease in contrast was also observed when reducing the number of frame averages. The optimal settings for the low-dose acquisition mode with respect to image quality and dose were found to be one reset frame and three frame averages. All patients at the Northern Ireland Cancer Centre are now imaged using one reset frame and three frame averages in the 6 MV 100 MU min(-1) low-dose acquisition mode. Routine EPID QC contrast tolerance (+/-10) and action (+/-20) levels using the PIPSPro phantom based around expected values of 190 (Varian 600C/D) and 225 (Varian 2100C/D) have been introduced. The dose at dmax from electronic portal imaging has been reduced by approximately 28%, and while the image quality has been reduced, the images produced are still clinically acceptable.

摘要

本研究旨在调查电子射野影像(EPI)采集过程是否能够优化,从而为PIPSPro QC-3V模体图像质量评估设定耐受水平和行动水平。优化过程的目的是在保持临床可接受图像质量的同时,减少对患者的辐射剂量。当在计划的患者治疗之外采集图像,而非在患者治疗期间使用治疗野采集图像时,这一点很重要。使用一系列模体,相对于验收测试后获得的基线值,评估不同采集设置下的图像质量。比较了四台匹配的Varian 600C/D直线加速器和四台匹配的Varian 2100C/D直线加速器上的八台Varian aS500 EPID系统的性能一致性,并在四个主要正交机架角度采集图像。使用6 MV射线束,以100 MU min⁻¹的剂量率和低剂量采集模式采集图像。比较中使用的剂量通过置于固体水模体中d(max)处的 Farmer电离室进行测量。结果表明,重置帧数对图像对比度没有任何影响,但帧平均次数有影响。在减少帧平均次数时,还观察到了噪声预期增加而对比度相应降低的情况。发现低剂量采集模式在图像质量和剂量方面的最佳设置为1次重置帧和3次帧平均。现在,北爱尔兰癌症中心的所有患者在6 MV 100 MU min⁻¹低剂量采集模式下成像时均使用1次重置帧和3次帧平均。基于190(Varian 600C/D)和225(Varian 2100C/D)的预期值,引入了使用PIPSPro模体的常规EPID QC对比度耐受水平(±10)和行动水平(±20)。电子射野影像在dmax处的剂量降低了约28%,虽然图像质量有所下降,但生成的图像在临床上仍然是可接受的。

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