Kavuma Awusi, Glegg Martin, Currie Garry, Elliott Alex
Department of Radiotherapy Physics, Beatson West of Scotland Cancer Center, NHS Greater Glasgow & Clyde, 1053 Great Western Road, Glasgow G12 0YN Scotland, UK.
Phys Med Biol. 2008 Dec 7;53(23):6893-909. doi: 10.1088/0031-9155/53/23/016. Epub 2008 Nov 12.
Dosimetrical characteristics of 11 Varian a-Si-500 electronic portal imaging devices (EPIDs) in clinical use for periods ranging between 10 and 86 months were investigated for consistency of performance and portal dosimetry implications. Properties studied include short-term reproducibility, signal linearity with monitor units, response to reference beam, signal uniformity across the detector panel, signal dependence on field size, dose-rate influence, memory effects and image profiles as a function of monitor units. The EPID measurements were also compared with those of the ionization chambers' to ensure stability of the linear accelerators. Depending on their clinical installation date, the EPIDs were interfaced with one of the two different acquisition control software packages, IAS2/IDU-II or IAS3/IDU-20. Both the EPID age and image acquisition system influenced the dosimetric characteristics with the newer version (IAS3 with IDU-20) giving better data reproducibility and linearity fit than the older version (IAS2 with IDU-II). The relative signal response (uniformity) after 50 MU was better than 95% of the central value and independent of detector. Sensitivity for all EPIDs reduced continuously with increasing dose rates for the newer image acquisition software. In the dose-rate range 100-600 MU min(-1), the maximum variation in sensitivity ranged between 1 and 1.8% for different EPIDs. For memory effects, the increase in the measured signal at the centre of the irradiated field for successive images was within 1.8% and 1.0% for the older and newer acquisition systems, respectively. Image profiles acquired at a lower MU in the radial plane (gun-target) had gradients in measured pixel values of up to 25% for the older system. Detectors with software/hardware versions IAS3/IDU-20 have a high degree of accuracy and are more suitable for routine quantitative IMRT dosimetrical verification.
研究了11台临床使用10至86个月的瓦里安a-Si-500电子射野影像装置(EPID)的剂量学特性,以评估其性能一致性和射野剂量学影响。研究的特性包括短期重复性、与监测单位的信号线性、对参考束的响应、探测器面板上的信号均匀性、信号对射野大小的依赖性、剂量率影响、记忆效应以及作为监测单位函数的图像轮廓。还将EPID测量结果与电离室的测量结果进行比较,以确保直线加速器的稳定性。根据临床安装日期,EPID与两种不同的采集控制软件包之一IAS2/IDU-II或IAS3/IDU-20连接。EPID的使用年限和图像采集系统都会影响剂量学特性,较新版本(IAS3与IDU-20)的数据再现性和线性拟合比旧版本(IAS2与IDU-II)更好。50MU后的相对信号响应(均匀性)优于中心值的95%,且与探测器无关。对于较新的图像采集软件,所有EPID的灵敏度都随着剂量率的增加而持续降低。在100 - 600MU min(-1)的剂量率范围内,不同EPID的灵敏度最大变化在1%至1.8%之间。对于记忆效应,连续图像中照射野中心测量信号的增加,旧采集系统和新采集系统分别在1.8%和1.0%以内。旧系统在径向平面(电子枪 - 靶)以较低MU采集的图像轮廓,测量像素值的梯度高达25%。具有软件/硬件版本IAS3/IDU-20的探测器具有高度准确性,更适合常规定量调强放疗剂量学验证。