Toprak Omer
Department of Nephrology, Ataturk Training and Research Hospital, Izmir, Turkey.
Am J Med Sci. 2007 Oct;334(4):283-90. doi: 10.1097/MAJ.0b013e318068ddf9.
Radiological procedures requiring intravascular administration of iodinated contrast media are becoming a common source of an iatrogenic disease known as contrast-induced nephropathy (CIN). The treatment of established CIN is limited to supportive measures and dialysis. Therefore, identifying high-risk patients is the first step to minimize the overall risk of CIN. The purpose of this review is to describe classic and possible risk markers of CIN according to the ultimate clinical research and developments. Original publications, review articles, papers from our personal library, and guidelines on CIN were reviewed. Terms used for PubMed and Medline searches were as follows: "contrast-induced nephropathy," "radio-contrast nephropathy," "contrast nephropathy," "contrast medium-induced nephropathy," "contrast media," and "risk factors." No restriction was placed on date of publication. Preexisting renal failure, especially when secondary to diabetic nephropathy, is the most important risk marker for CIN.
需要血管内注射碘化造影剂的放射学检查正成为一种医源性疾病（称为造影剂肾病，CIN）的常见病因。已确诊的CIN的治疗仅限于支持性措施和透析。因此，识别高危患者是将CIN总体风险降至最低的第一步。本综述的目的是根据最终的临床研究和进展描述CIN的经典和可能的风险标志物。我们检索了原始出版物、综述文章、个人藏书论文以及CIN相关指南。用于PubMed和Medline检索的术语如下：“造影剂肾病”、“放射性造影剂肾病”、“造影剂肾病”、“造影剂诱导的肾病”、“造影剂”和“危险因素”。对出版日期未作限制。既往存在肾衰竭，尤其是继发于糖尿病肾病时，是CIN最重要的风险标志物。
