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与加纳局部疾病暴发相关的一种新型利什曼原虫的证据。

Evidence for a new species of Leishmania associated with a focal disease outbreak in Ghana.

作者信息

Villinski Jeffrey T, Klena John D, Abbassy Magda, Hoel David F, Puplampu Naiki, Mechta Sarah, Boakye Daniel, Raczniak Gregory

机构信息

US Naval Medical Research Unit No. 3, Cairo, Egypt.

出版信息

Diagn Microbiol Infect Dis. 2008 Mar;60(3):323-7. doi: 10.1016/j.diagmicrobio.2007.09.013. Epub 2007 Nov 26.

DOI:10.1016/j.diagmicrobio.2007.09.013
PMID:18031968
Abstract

A previously unknown Leishmania spp., inferred by DNA sequence analysis of the small subunit ribosomal RNA gene and the internal transcribed spacer region (ITS1), was detected in tissue biopsies from patients living in the Eastern Ghanaian community of Taviefe. Restriction fragment length polymorphism analysis of the ITS1 amplicon supports the possibility of an uncharacterized Leishmania spp.

摘要

通过对小亚基核糖体RNA基因和内部转录间隔区(ITS1)进行DNA序列分析,在居住于加纳东部塔维费社区的患者组织活检中检测到一种先前未知的利什曼原虫。ITS1扩增子的限制性片段长度多态性分析支持存在一种未鉴定的利什曼原虫的可能性。

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