Oie Shigeharu, Suenaga Shigeyuki, Sawa Akihiro, Kamiya Akira
Department of Pharmacy, Yamaguchi University Hospital, Ube 755-8505, Japan.
Jpn J Infect Dis. 2007 Nov;60(6):367-9.
In 106 inpatients with methicillin-resistant Staphylococcus aureus (MRSA)-positive body sites, MRSA contamination on their surrounding environmental surfaces and the palm of their dominant hand were detected and quantified. The association between MRSA-positive sites (palm of dominant hand, sputum, nasal discharge, pharyngeal mucosa, open pus, closed pus, urine, feces, and others) in patients and MRSA contamination in their surrounding environmental surfaces was evaluated by quantification theory II of multivariate analysis. The surrounding environmental surfaces were contaminated with MRSA in 54 (50.9%) of the 106 patients. The contamination of MRSA was 380.2 +/- 2,198.0 colony forming units (cfu)/100 cm(2) in 41 (40.2%) of 102 bed linen samples, 15.2 +/- 69.5 cfu/100 cm(2) in 19 (22.4%) of 85 overbed table samples, 12.8 +/- 56.5 cfu/about 100 cm(2) in 18 (20.9%) of 86 bed side rail samples, and 0.2 +/- 1.3 cfu/entire handle surface in 2 (2.7%) of 74 samples of room door handles on the inner side of the patients' room doors. In the palm, 6,743.3 +/- 65,446.5 cfu/palm MRSA was detected in 29 (29.6%) of 98 patients. MRSA in patients' palms had the most marked influence on MRSA contamination of their surrounding environmental surfaces. When MRSA is detected in patients' palms the possibility of MRSA contamination of their surrounding environmental surfaces is high.
在106例耐甲氧西林金黄色葡萄球菌（MRSA）阳性身体部位的住院患者中，对其周围环境表面和优势手手掌上的MRSA污染进行了检测和定量。通过多变量分析的量化理论II评估患者中MRSA阳性部位（优势手手掌、痰液、鼻涕、咽黏膜、开放性脓液、闭合性脓液、尿液、粪便等）与周围环境表面MRSA污染之间的关联。106例患者中有54例（50.9%）的周围环境表面被MRSA污染。102份床单样本中有41份（40.2%）的MRSA污染为380.2±2198.0菌落形成单位（cfu）/100 cm²，85份多功能床旁桌样本中有19份（22.4%）的污染为15.2±69.5 cfu/100 cm²，86份床边护栏样本中有18份（20.9%）的污染为12.8±56.5 cfu/约100 cm²，患者病房内侧74个房间门把手样本中有2份（2.7%）的污染为0.2±1.3 cfu/整个把手表面。在手掌方面，98例患者中有29例（29.6%）检测到6743.3±65446.5 cfu/手掌的MRSA。患者手掌中的MRSA对其周围环境表面的MRSA污染影响最为显著。当在患者手掌中检测到MRSA时，其周围环境表面被MRSA污染的可能性很高。
