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2007年日本群马县流行的麻疹病毒核蛋白(N)基因的序列及系统发育分析

Sequence and phylogenetic analysis of the nucleoprotein (N) gene in measles viruses prevalent in Gunma, Japan, in 2007.

作者信息

Morita Yukio, Suzuki Tomoyuki, Shiono Masataka, Shiobara Masae, Saitoh Mika, Tsukagoshi Hiroyuki, Yoshizumi Masakazu, Ishioka Taisei, Kato Masahiko, Kozawa Kunihisa, Ttanaka-Taya Keiko, Yasui Yoshinori, Noda Masahiro, Okabe Nobuhiko, Kimura Hirokazu

机构信息

Gunma Prefectural Institute of Public Health and Environmental Sciences, Gunma, Japan.

出版信息

Jpn J Infect Dis. 2007 Nov;60(6):402-4.

Abstract

In 2007, relatively large outbreaks of measles occurred in the Kanto region of Japan, including Gunma Prefecture. We performed sequence and phylogenetic analysis of the nucleoprotein gene (N gene) of measles viruses from 3 measles patients in this area in May 2007. The N gene sequences of the present strains were identical to each other, and phylogenetic analysis showed these viruses were classified into genotype D5. The results suggest that highly homologous measles viruses may be associated with outbreaks of measles in Gunma, Japan.

摘要

2007年,日本关东地区,包括群马县,发生了规模相对较大的麻疹疫情。我们对2007年5月该地区3名麻疹患者的麻疹病毒核蛋白基因(N基因)进行了序列和系统发育分析。当前菌株的N基因序列彼此相同,系统发育分析表明这些病毒被归类为D5基因型。结果表明,高度同源的麻疹病毒可能与日本群马县的麻疹疫情有关。

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