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[对感染灭活马尔堡病毒的豚鼠免疫指标的比较研究]

[A comparative study of the immunological indices in guinea pigs administered an inactivated Marburg virus].

作者信息

Ignat'ev G M, Agafonov A P, Strel'tsova M A, Kuz'min V A, Maĭnagasheva G I, Spirin G V, Chernyĭ N B

出版信息

Vopr Virusol. 1991 Sep-Oct;36(5):421-3.

PMID:1803779
Abstract

Samples of concentrated and unconcentrated preparations of Marburg virus were studied. The ultrafiltration method helped increase the specific protein content and decrease the common protein content in a preparation. The resistance index increased with an increase of the specific protein content and the maximum (2.63 +/- 0.2) was reached by two immunizations on 0 and 14 days.

摘要

对马尔堡病毒浓缩制剂和未浓缩制剂的样本进行了研究。超滤法有助于提高制剂中特定蛋白质的含量并降低普通蛋白质的含量。抗性指数随着特定蛋白质含量的增加而增加,在第0天和第14天进行两次免疫后达到最大值(2.63±0.2)。

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