Brotherton Helen, Philip Roy K
Mid-Western Regional and Maternity Hospitals, Limerick, Ireland.
Eur J Pediatr. 2008 Jan;167(1):43-6. doi: 10.1007/s00431-007-0423-1. Epub 2007 Feb 16.
Anomalous left coronary artery from pulmonary artery (ALCAPA) is a rare congenital cardiac malformation. It presents predominantly in infancy with features of myocardial ischaemia or cardiac failure and may be mistaken for common paediatric conditions such as colic, reflux or bronchiolitis. With early surgical correction the prognosis is good, but awareness of this condition is essential for prompt diagnosis and referral to a tertiary cardiac centre. In this report we review the five cases that presented during our 5-year study period and discuss the incidence and clinical presentation of ALCAPA among infants. Our observed incidence of 1 in 4243 live births--0.023%--is higher than previously reported. ALCAPA may be more common than previously recognised, and there should be a high index of awareness among paediatricians, paediatric trainees and general practitioners to enable early surgical intervention and improved prognosis for these children.
起源于肺动脉的异常左冠状动脉（ALCAPA）是一种罕见的先天性心脏畸形。它主要在婴儿期出现，表现为心肌缺血或心力衰竭的特征，可能被误诊为常见的儿科疾病，如绞痛、反流或支气管炎。早期手术矫正预后良好，但认识到这种疾病对于及时诊断并转诊至三级心脏中心至关重要。在本报告中，我们回顾了在我们5年研究期间出现的5例病例，并讨论了婴儿中ALCAPA的发病率和临床表现。我们观察到的活产发病率为4243例中有1例——0.023%——高于先前报道。ALCAPA可能比以前认为的更常见，儿科医生、儿科实习生和全科医生应高度警惕，以便能够对这些儿童进行早期手术干预并改善预后。
