Santhanam R, Pillai Shibu V, Kolluri Sastry V R, Rao U M
Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bangalore-560 029, India.
Neurol India. 2007 Oct-Dec;55(4):349-54. doi: 10.4103/0028-3886.37094.
Head injury contributes significantly to mortality and morbidity in India. Evaluation of the available trauma care facilities may help improve outcome.
To evaluate the factors influencing the mortality of patients with head injury who had intensive care management and evolve strategies to improve outcome.
Retrospective study in a tertiary hospital where intracranial pressure monitoring (ICPM) is not routinely practiced.
All patients with head injury managed in the intensive care unit in a two-year period were included. The factors evaluated were age, vital signs, Glasgow Coma scale score (GCS) at admission, pupillary light reflex (PR), oculocephalic reflex (OCR), hemodynamic stability, computerized tomography (CT) findings, diabetes mellitus, anemia, infections and abnormalities of serum sodium.
We analyzed 208 patients (202 without ICPM). In-hospital mortality was 64 (31%). Only 24 (11.5%) patients were admitted within one hour of injury, while one-third arrived after six hours. The clinical factors (at admission) that influenced mortality included age, GCS, PR, OCR and diastolic blood pressure (DBP). Effacement of the basal cisterns in the initial and repeat CT scans, hyperglycemia, hemodynamic instability and serum sodium imbalances were associated with higher mortality. The independent predictors of mortality by logistic regression were initial GCS, DBP, hemodynamic instability and effacement of cisterns on repeat CT.
Mortality following head injury is high. Pre-hospital emergency medical services are disorganized. The key to reducing mortality within the limitations of our current trauma system is maintenance of DBP>70 mmHg and SBP>90 mmHg from the time of first contact.
在印度,头部损伤是导致死亡率和发病率的重要因素。评估现有的创伤护理设施可能有助于改善治疗结果。
评估影响接受重症监护管理的头部损伤患者死亡率的因素,并制定改善治疗结果的策略。
在一家未常规进行颅内压监测(ICPM)的三级医院进行回顾性研究。
纳入在两年期间在重症监护病房接受治疗的所有头部损伤患者。评估的因素包括年龄、生命体征、入院时的格拉斯哥昏迷量表评分(GCS)、瞳孔光反射(PR)、眼头反射(OCR)、血流动力学稳定性、计算机断层扫描(CT)结果、糖尿病、贫血、感染和血清钠异常。
我们分析了208例患者(202例未进行ICPM)。住院死亡率为64例(31%)。只有24例(11.5%)患者在受伤后1小时内入院,而三分之一的患者在6小时后到达。影响死亡率的临床因素(入院时)包括年龄、GCS、PR、OCR和舒张压(DBP)。初次和重复CT扫描中基底池消失、高血糖、血流动力学不稳定和血清钠失衡与较高的死亡率相关。逻辑回归分析得出的死亡率独立预测因素为初始GCS、DBP、血流动力学不稳定和重复CT扫描时基底池消失。
头部损伤后的死亡率很高。院前紧急医疗服务混乱。在我们当前创伤系统的限制范围内降低死亡率的关键是从首次接触时起维持DBP>70 mmHg和SBP>90 mmHg。