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Psychoactive drug effects on a system which generates cyclic AMP in brain.

作者信息

Schultz J

出版信息

Nature. 1976 Jun 3;261(5559):417-8. doi: 10.1038/261417a0.

DOI:10.1038/261417a0
PMID:180412
Abstract
摘要

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1
Psychoactive drug effects on a system which generates cyclic AMP in brain.精神活性药物对大脑中产生环磷酸腺苷的系统的影响。
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The cyclic AMP response to noradrenalin in young adult rat brain following post-natal injections of 6-hydroxydopamine.出生后注射6-羟基多巴胺后,成年幼鼠大脑中去甲肾上腺素对环磷酸腺苷的反应。
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Modification by psychotropic drugs of the cyclic AMP response to norepinephrine in the rat brain in vitro.精神药物对体外培养的大鼠脑中去甲肾上腺素引起的环磷酸腺苷反应的修饰作用。
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Cyclic AMP in brain areas: effects of amphetamine and norepinephrine assessed through the use of microwave radiation as a means of tissue fixation.
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No change in rat cerebral cortex calmodulin content following chronic treatment with lithium, reserpine, imipramine, and lithium combined with reserpine or imipramine.用锂、利血平、丙咪嗪以及锂与利血平或丙咪嗪联合长期治疗后,大鼠大脑皮层钙调蛋白含量无变化。
Acta Pharmacol Toxicol (Copenh). 1984 May;54(5):394-9. doi: 10.1111/j.1600-0773.1984.tb01948.x.

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Effects of subchronic administration of antidepressants and anxiolytics on levels of the alpha subunits of G proteins in the rat brain.亚慢性给予抗抑郁药和抗焦虑药对大鼠脑内G蛋白α亚基水平的影响。
J Neural Transm (Vienna). 1997;104(6-7):747-60. doi: 10.1007/BF01291891.
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Behavioural changes during withdrawal from desmethylimipramine (DMI). I. Interactions with amphetamine.去甲丙咪嗪(DMI)戒断期间的行为变化。I. 与苯丙胺的相互作用。
Psychopharmacology (Berl). 1981;75(1):54-9. doi: 10.1007/BF00433502.
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Potentiation of the action of adenosine on cerebral cortical neurones by the tricyclic antidepressants.
三环类抗抑郁药对腺苷作用于大脑皮质神经元的增强作用。
Br J Pharmacol. 1984 Oct;83(2):567-75. doi: 10.1111/j.1476-5381.1984.tb16521.x.
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The effect of chronic treatment with antidepressant drugs on salbutamol-induced hypoactivity in rats.抗抑郁药物长期治疗对大鼠沙丁胺醇诱导的活动减退的影响。
Psychopharmacology (Berl). 1983;80(4):355-9. doi: 10.1007/BF00432120.
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Effect of destruction of central noradrenergic and serotonergic nerve terminals by systemic neurotoxins on the long-term effects of antidepressants on beta-adrenoceptors and 5-HT2 binding sites in the rat cerebral cortex.全身神经毒素对大鼠大脑皮质中去甲肾上腺素能和5-羟色胺能神经末梢的破坏作用对抗抑郁药对β-肾上腺素能受体和5-HT2结合位点长期影响的研究
J Neural Transm. 1984;59(1):9-23. doi: 10.1007/BF01249875.
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Sensitivity in vivo of central alpha 2- and opiate receptors after chronic treatment with various antidepressants.多种抗抑郁药长期治疗后中枢α2受体和阿片受体的体内敏感性
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The noradrenaline receptor coupled adenylate cyclase system in brain. Lack of modification by changes in the availability of serotonin.大脑中去甲肾上腺素受体偶联的腺苷酸环化酶系统。不受血清素可用性变化的影响。
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Development of and recovery from subsensitivity of the noradrenergic cyclic AMP generating system in brain. Effect of amphetamine following inhibition of its aromatic hydroxylation by iprindole.脑中去甲肾上腺素能环磷酸腺苷生成系统的亚敏感性的发展及恢复。异吲哚抑制苯丙胺芳香羟化后苯丙胺的作用。
Naunyn Schmiedebergs Arch Pharmacol. 1980 Aug;313(2):113-8. doi: 10.1007/BF00498565.
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Effects of zimelidine on serotoninergic and noradrenergic neurons after repeated administration in the rat.大鼠反复给药后齐美利定对5-羟色胺能和去甲肾上腺素能神经元的影响。
Psychopharmacology (Berl). 1981;72(3):219-25. doi: 10.1007/BF00431820.
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Antagonism of behavioural depression produced by clonidine in the Mongolian gerbil: a potential screening test for antidepressant drugs.
Psychopharmacology (Berl). 1983;79(2-3):203-8. doi: 10.1007/BF00427813.