Okamoto Hitoshi
Laboratory for Developmental Gene Regulation, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
ACS Chem Biol. 2007 Oct 19;2(10):646-8. doi: 10.1021/cb700213e.
Molecular biologists have long dreamed of switching genes on and off at will in any part of the body during embryonic development. Their dream is now coming true thanks to the transparency of the embryonic body of the zebrafish ( Danio rerio), which has made gene manipulation by photoillumination possible.
长期以来,分子生物学家一直梦想着在胚胎发育过程中,能随意控制身体任何部位的基因开关。如今,他们的梦想正在实现,这要归功于斑马鱼(Danio rerio)胚胎身体的透明性,这使得通过光照进行基因操作成为可能。