Tan Jerry K L, Tang Jing, Fung Karen, Gupta Aditya K, Thomas D Richard, Sapra Sheetal, Lynde Charles, Poulin Yves, Gulliver Wayne, Sebaldt Rolf J
University of Western Ontario, London, ON, Canada.
J Cutan Med Surg. 2007 Nov-Dec;11(6):211-6. doi: 10.2310/7750.2007.00037.
Although more than 25 acne grading systems exist, only 2 are inclusive of truncal acne. There is neither a gold standard nor a consistently used standardized system.
Our purpose was to develop and validate an acne grading system incorporating severity at the face, chest, and back.
We developed a comprehensive acne severity scale (CASS) by modifying a preexisting facial acne scale, the Investigator Global Assessment, to include truncal acne. The validity and responsiveness of CASS grades were correlated with Leeds scores at baseline and after 6 months of standard acne treatment.
Spearman correlations were significant between Leeds and CASS grades for the face (0.823), chest (0.854), and back (0.872), respectively (p < .001). After 6 months of therapy, changes in these scores were also significantly correlated (p < .001) at all three sites.
Concurrent validity of CASS is demonstrated by a very strong correlation with Leeds grading. CASS is simpler to use than the Leeds system and more appropriate for translation of research trial results to clinical practice.
虽然存在超过25种痤疮分级系统,但只有2种包含躯干痤疮。既没有金标准,也没有一直被使用的标准化系统。
我们的目的是开发并验证一种纳入面部、胸部和背部严重程度的痤疮分级系统。
我们通过修改已有的面部痤疮量表——研究者整体评估,开发了一种综合痤疮严重程度量表(CASS),以纳入躯干痤疮。CASS分级的有效性和反应性与基线时以及标准痤疮治疗6个月后的利兹评分相关。
利兹评分与CASS分级在面部(0.823)、胸部(0.854)和背部(0.872)的斯皮尔曼相关性分别显著(p < .001)。治疗6个月后,所有三个部位这些评分的变化也显著相关(p < .001)。
CASS与利兹分级的高度相关性证明了其同时效度。CASS比利兹系统更易于使用,更适合将研究试验结果转化为临床实践。