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一种综合性痤疮严重程度量表的开发与验证

Development and validation of a comprehensive acne severity scale.

作者信息

Tan Jerry K L, Tang Jing, Fung Karen, Gupta Aditya K, Thomas D Richard, Sapra Sheetal, Lynde Charles, Poulin Yves, Gulliver Wayne, Sebaldt Rolf J

机构信息

University of Western Ontario, London, ON, Canada.

出版信息

J Cutan Med Surg. 2007 Nov-Dec;11(6):211-6. doi: 10.2310/7750.2007.00037.

Abstract

BACKGROUND

Although more than 25 acne grading systems exist, only 2 are inclusive of truncal acne. There is neither a gold standard nor a consistently used standardized system.

PURPOSE

Our purpose was to develop and validate an acne grading system incorporating severity at the face, chest, and back.

METHODS

We developed a comprehensive acne severity scale (CASS) by modifying a preexisting facial acne scale, the Investigator Global Assessment, to include truncal acne. The validity and responsiveness of CASS grades were correlated with Leeds scores at baseline and after 6 months of standard acne treatment.

RESULTS

Spearman correlations were significant between Leeds and CASS grades for the face (0.823), chest (0.854), and back (0.872), respectively (p < .001). After 6 months of therapy, changes in these scores were also significantly correlated (p < .001) at all three sites.

CONCLUSION

Concurrent validity of CASS is demonstrated by a very strong correlation with Leeds grading. CASS is simpler to use than the Leeds system and more appropriate for translation of research trial results to clinical practice.

摘要

背景

虽然存在超过25种痤疮分级系统,但只有2种包含躯干痤疮。既没有金标准,也没有一直被使用的标准化系统。

目的

我们的目的是开发并验证一种纳入面部、胸部和背部严重程度的痤疮分级系统。

方法

我们通过修改已有的面部痤疮量表——研究者整体评估,开发了一种综合痤疮严重程度量表(CASS),以纳入躯干痤疮。CASS分级的有效性和反应性与基线时以及标准痤疮治疗6个月后的利兹评分相关。

结果

利兹评分与CASS分级在面部(0.823)、胸部(0.854)和背部(0.872)的斯皮尔曼相关性分别显著(p < .001)。治疗6个月后,所有三个部位这些评分的变化也显著相关(p < .001)。

结论

CASS与利兹分级的高度相关性证明了其同时效度。CASS比利兹系统更易于使用,更适合将研究试验结果转化为临床实践。

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