Guerra-Tapia A, Puig-Sanz L, Conejo Mir J, Toribio-Pérez J, Iglesias C, Zsolt I
Servicio de Dermatología, Hospital Universitario 12 de Octubre, Madrid, España.
Actas Dermosifiliogr. 2010 Nov;101(9):778-84.
Although there are more than 25 acne grading systems, there is no consensus on which is most appropriate. Unification of the classifications is recommended in order to facilitate therapeutic decisions.
To assess the feasibility and reliability of the Spanish version of the Leeds revised acne grading (LRAG) scale in patients with acne vulgaris in Spain.
We conducted a prospective, multicenter, observational study in Spain, including patients with acne affecting at least 1 of 3 regions: face, back, or chest. Patients were assessed using the LRAG scale and lesion counting. Changes in the scores were determined at 4-6 weeks, and were correlated with the lesion count. Physicians were asked 4 questions regarding difficulty using the scale and the time employed.
A total of 259 sites of acne were assessed in 239 patients at 57 centers. The majority of physicians (89.5%) stated that the LRAG scale was not difficult to use. The mean administration time was 3.12min. Cross-sectional validity (P<.012 for the face, P<.001 for the back and chest), longitudinal validity (P<.0001 for the face, back, and chest), and intraobserver and interobserver reliability (Cronbach α >0.8) were significant for inflammatory lesions in all regions. Sensitivity to change was demonstrated for lesions in all regions, based on the correlation between the difference in severity and the number of lesions recorded by the LRAG, and the difference in the lesion count between baseline and follow-up.
The Spanish version of the LRAG scale is a practical and reliable tool and is sensitive to change. It is a valid tool for the objective assessment of the severity of acne.
尽管有超过25种痤疮分级系统，但对于哪种最为合适尚无共识。建议统一分类以促进治疗决策。
评估西班牙版利兹修订痤疮分级（LRAG）量表在西班牙寻常痤疮患者中的可行性和可靠性。
我们在西班牙进行了一项前瞻性、多中心、观察性研究，纳入痤疮累及面部、背部或胸部这3个区域中至少1个区域的患者。使用LRAG量表和皮损计数对患者进行评估。在4 - 6周时确定评分变化，并与皮损计数相关联。就使用该量表的难度和所花费时间向医生询问了4个问题。
在57个中心的239例患者中，共评估了259处痤疮部位。大多数医生（89.5%）表示LRAG量表不难使用。平均使用时间为3.12分钟。所有区域炎性皮损的横断面效度（面部P<0.012，背部和胸部P<0.001）、纵向效度（面部、背部和胸部P<0.0001）以及观察者内和观察者间信度（Cronbach α>0.8）均显著。基于LRAG记录的严重程度差异与皮损数量之间的相关性以及基线和随访之间的皮损计数差异，所有区域的皮损均显示出对变化的敏感性。
西班牙版LRAG量表是一种实用且可靠的工具，对变化敏感。它是客观评估痤疮严重程度的有效工具。
