Layton Alison M, Gupta Girish, Seukeran Daron, Maruthappu Thivi, Gaillard Stephanie, Whitehouse Heather, Ali Faisal R, Razzaque Angelika, Al-Niaimi Firas, Copperwheat Sarah
Skin Research Centre, University of York, Heslington Road, York, YO10 5DD, UK.
Edinburgh Royal Infirmary, Edinburgh, Scotland, UK.
Dermatol Ther (Heidelb). 2024 Oct;14(10):2727-2738. doi: 10.1007/s13555-024-01275-0. Epub 2024 Sep 21.
Acne remains one of the most common inflammatory dermatoses seen worldwide. There are significant challenges when managing acne relating to a variety of factors, including (1) lack of consensus on the use of the numerous available grading systems and outcome measures, (2) appreciation of the numerous areas that relate to severity, (3) the chronic nature of acne which requires a longitudinal approach to management (including both facial and truncal disease), and (4) the need to target acne early to avoid physical and psychosocial scarring. Consideration of these aspects when managing acne should result in improved outcomes. Acne guidelines review the available evidence based on robust clinical trials and are usually supplemented with some expert opinion when evidence is not available.
In this paper, the UK Acne Working Group reflects on the latest National Institute for Health and Care Excellence (NICE) acne guidelines with a goal of providing additional practical insights.
The group have identified areas where new evidence has now become available since the formulation of the NICE acne guidelines. This publication considers newly approved acne medications in the UK, guidance on assessing acne severity, approaches to managing truncal acne, acne sequelae, and adult female acne with hormonal therapies.
痤疮仍然是全球最常见的炎症性皮肤病之一。在痤疮管理方面存在诸多重大挑战，涉及多种因素，包括：（1）对于众多可用的分级系统和疗效评估指标的使用缺乏共识；（2）对与严重程度相关的众多方面的认识；（3）痤疮的慢性性质需要采用纵向管理方法（包括面部和躯干疾病）；（4）需要尽早针对痤疮进行治疗以避免身体和心理社会方面的瘢痕形成。在痤疮管理中考虑这些方面应能改善治疗效果。痤疮指南会基于可靠的临床试验对现有证据进行审查，并且在缺乏证据时通常会补充一些专家意见。
在本文中，英国痤疮工作组对最新的英国国家卫生与临床优化研究所（NICE）痤疮指南进行反思，目的是提供更多实用见解。
该小组确定了自NICE痤疮指南制定以来已出现新证据的领域。本出版物探讨了英国新批准的痤疮药物、痤疮严重程度评估指南、躯干痤疮管理方法、痤疮后遗症以及激素疗法治疗成年女性痤疮的情况。
