Du Na, Hou Wan-Guo, Song Shu-E
Key Laboratory for Colloid and Interface Chemistry of Education Ministry, Shandong University, Jinan 250100, People's Republic of China.
J Phys Chem B. 2007 Dec 20;111(50):13909-13. doi: 10.1021/jp076230i. Epub 2007 Nov 29.
We report a novel composite: layered double hydroxides (LDHs) encapsulated in vesicles. It was found that positively charged Mg3Al-LDH nanoparticles can induce the spontaneous formation of vesicles in a mixture of a zwitterionic surfactant, dodecyl betaine (C12BE), and an anionic surfactant, sodium bis(2-ethylhexyl) sulfosuccinate (AOT), and importantly, we obtain simultaneously a novel composite of Mg3Al-LDH encapsulated in vesicles. The obtained composite is very stable and expected to be potentially used in drug delivery and gene therapy.