老年患者癌症手术的风险评估
Risk assessment for cancer surgery in elderly patients.
作者信息
Ramesh Hodigere S J, Boase Tom, Audisio Riccardo A
机构信息
Department of Surgery,Whiston Hospital, Prescot, Liverpool, Merseyside, UK.
出版信息
Clin Interv Aging. 2006;1(3):221-7. doi: 10.2147/ciia.2006.1.3.221.
Abstract
Global growth of the elderly population is requiring healthcare providers to cater for an expanding elderly cancer subpopulation. The aggression with which cancer should be treated in this subpopulation is an ethical dilemma and is an ongoing debate, as surgeons have feared increases in postoperative morbidity and mortality. As a result elderly patients often receive suboptimal cancer treatment. The need for standardization of cancer surgery is well recognized despite the difficulties in view of heterogeneity of the group. In this article, epidemiological changes, tumor biology specific to elderly cancer are visited, operative risk assessment tools are discussed, and interim results of ongoing multinational investigation ie, PACE (Preoperative Assessment of Cancer Elderly) revealed.
摘要
全球老年人口的增长要求医疗保健提供者为不断扩大的老年癌症亚群体提供服务。对于该亚群体中的癌症应采取何种积极治疗方式是一个伦理困境，并且仍在持续争论中，因为外科医生担心术后发病率和死亡率会增加。因此，老年患者往往接受的是次优的癌症治疗。尽管鉴于该群体的异质性存在困难，但癌症手术标准化的需求已得到广泛认可。在本文中，探讨了流行病学变化、老年癌症特有的肿瘤生物学，讨论了手术风险评估工具，并展示了正在进行的多国研究（即PACE，老年癌症术前评估）的中期结果。
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