关节负荷方式：其在骨形成和骨折愈合中的应用。
Joint loading modality: its application to bone formation and fracture healing.
作者信息
Zhang P, Malacinski G M, Yokota H
机构信息
Department of Biomedical Engineering, Indiana University Purdue University Indianapolis, Fesler Hall 115, 1120 South Drive, Indianapolis, IN 46202, USA.
出版信息
Br J Sports Med. 2008 Jul;42(7):556-60. doi: 10.1136/bjsm.2007.042556. Epub 2007 Nov 29.
Abstract
Sports-related injuries such as impact and stress fractures often require a rehabilitation programme to stimulate bone formation and accelerate fracture healing. This review introduces a recently developed joint loading modality and evaluates its potential applications to bone formation and fracture healing in post-injury rehabilitation. Bone is a dynamic tissue whose structure is constantly altered in response to its mechanical environments. Indeed, many loading modalities can influence the bone remodelling process. The joint loading modality is, however, able to enhance anabolic responses and accelerate wound healing without inducing significant in situ strain at the site of bone formation or fracture healing. This review highlights the unique features of this loading modality and discusses its potential underlying mechanisms as well as possible clinical applications.
摘要
与运动相关的损伤，如冲击性骨折和应力性骨折，通常需要康复计划来刺激骨形成并加速骨折愈合。本综述介绍了一种最近开发的关节加载方式，并评估了其在损伤后康复中对骨形成和骨折愈合的潜在应用。骨是一种动态组织，其结构会根据其力学环境不断改变。事实上，许多加载方式都能影响骨重塑过程。然而，关节加载方式能够增强合成代谢反应并加速伤口愈合，而不会在骨形成或骨折愈合部位引起显著的原位应变。本综述强调了这种加载方式的独特特征，并讨论了其潜在的潜在机制以及可能的临床应用。
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