Evaluation of denture cleansers with and without enzymes against Candida albicans.

The fungicidal effect on Candida albicans was evaluated for denture cleansers with and without enzymes (alkaline peroxide type). Three cleansers with proteolytic enzymes showed little yeast lytic ability, while one cleanser with yeast lytic and proteolytic enzymes and one cleanser without enzymes showed slight yeast lytic ability. The results suggested that the activity depended on alkaline peroxide rather than on enzymes. Five denture cleansers showed strong effects.