Labouesse Michel
Institut de Génétique et de Biologie Moléculaire et Cellulaire CNRS/INSERM/ULP, BP 10142, 67404 Illkirch Cedex France.
WormBook. 2006 Jan 13:1-21. doi: 10.1895/wormbook.1.56.1.
A distinctive feature of polarized epithelial cells is their specialized junctions, which contribute to cell integrity and provide platforms to orchestrate cell shape changes. The chapter discusses the composition and assembly of C. elegans cell-cell and cell-extracellular matrix junctions, proteins that anchor the cytoskeleton and mechanisms involved in establishing epithelial polarity. The focus remains cellular and does not properly deal with epithelial cells in the context of the developing embryo.
极化上皮细胞的一个显著特征是其特化的连接，这些连接有助于细胞完整性，并为协调细胞形状变化提供平台。本章讨论了秀丽隐杆线虫细胞间和细胞与细胞外基质连接的组成与组装、锚定细胞骨架的蛋白质以及建立上皮极性所涉及的机制。重点仍在细胞层面，并未在发育胚胎的背景下妥善处理上皮细胞。
