Käll Lukas, Storey John D, MacCoss Michael J, Noble William Stafford
Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA.
J Proteome Res. 2008 Jan;7(1):40-4. doi: 10.1021/pr700739d. Epub 2007 Dec 4.
A variety of methods have been described in the literature for assigning statistical significance to peptides identified via tandem mass spectrometry. Here, we explain how two types of scores, the q-value and the posterior error probability, are related and complementary to one another.
文献中已经描述了多种用于确定通过串联质谱鉴定的肽段的统计学显著性的方法。在此,我们解释两种类型的得分,即q值和后验错误概率,是如何相互关联且相互补充的。