Le Duff Michel J, Amstutz Harlan C, Dorey Frederick J
Joint Replacement Institute, 2400 South Flower Street, Los Angeles, CA 90007, USA.
J Bone Joint Surg Am. 2007 Dec;89(12):2705-11. doi: 10.2106/JBJS.F.01563.
The effect of obesity on the outcomes of metal-on-metal resurfacing arthroplasty is not currently known. In this study, we assessed the influence of body mass index on the survival of a metal-on-metal hybrid hip resurfacing prosthesis by comparing the clinical results of patients with a body mass index of >or=30 with those of patients with a body mass index of <30.
We retrospectively reviewed our registry to identify all patients who had been followed for at least two years after a metal-on-metal hip resurfacing arthroplasty, and we divided those patients according to whether they had had a body mass index of >or=30 (the study group) or <30 (the control group) at the time of the surgery. One hundred and twenty-five patients (144 hips) with an average weight of 104.6 kg and an average body mass index of 33.4 were included in the study group, and 531 patients (626 hips) with an average weight of 78.3 kg and an average body mass index of 25.4 were included in the control group. We compared the clinical results (UCLA [University of California at Los Angeles] and Harris hip scores, SF-12 [Short Form-12] survey results, and complication rates), radiographic results, and prosthetic survival rates of the two groups.
There was no significant difference postoperatively between the groups with regard to the UCLA pain or walking scores or the mental component score of the SF-12. However, the UCLA function and activity scores were lower in the study group than in the control group (9.2 compared with 9.6 points [p = 0.001] and 7.1 compared with 7.6 points [p = 0.002], respectively). The control group had a significantly higher postoperative physical component score on the SF-12 (51.4 points compared with 49.3 points in the study group, p = 0.01) and postoperative Harris hip score (93.8 compared with 90.6 points, p = 0.0003). Two hips (1.4%) were revised in the study group. In contrast, thirty-one hips (5.0%) were converted to a total hip replacement in the control group; twenty of the thirty-one were revised because of loosening of the femoral component. The five-year survivorship of the hip prostheses was 98.6% in the study group and 93.6% in the control group (p = 0.0401). When the entire cohort was divided into three groups according to whether the body mass index was <25, 25 to 29, or >or=30, the risk of revision was found to have decreased twofold from one group to the next as the body mass index increased (p = 0.013). No acetabular component loosened in either group. The average diameter of the femoral component was 48.3 mm in the study group and 46.8 mm in the control group (p = 0.0001). There were no revisions for any reason and no radiolucencies were observed in a subset of twenty-seven patients with a body mass index of >or=35.
Metal-on-metal resurfacing hip arthroplasty is performing well in patients with a high body mass index, although the function scores are reduced compared with those for patients with a body mass index of <30. The protective effect of a high body mass index on survivorship results may be explained by a reduced activity level and a greater component size in this patient population.
目前尚不清楚肥胖对金属对金属表面置换关节成形术预后的影响。在本研究中,我们通过比较体重指数≥30的患者与体重指数<30的患者的临床结果,评估体重指数对金属对金属混合髋关节表面置换假体生存率的影响。
我们回顾性分析了我们的登记资料,以确定所有在金属对金属髋关节表面置换关节成形术后至少随访两年的患者,并根据手术时他们的体重指数是否≥30(研究组)或<30(对照组)对这些患者进行分组。研究组纳入了125例患者(144髋),平均体重104.6kg,平均体重指数33.4;对照组纳入了531例患者(626髋),平均体重78.3kg,平均体重指数25.4。我们比较了两组的临床结果(加州大学洛杉矶分校[UCLA]和Harris髋关节评分、SF-12[简明健康调查简表-12]调查结果及并发症发生率)、影像学结果和假体生存率。
两组术后在UCLA疼痛或步行评分或SF-12的心理成分评分方面无显著差异。然而,研究组的UCLA功能和活动评分低于对照组(分别为9.2分对9.6分[p = 0.001]和7.1分对7.6分[p = 0.002])。对照组术后SF-12的身体成分评分显著更高(51.4分对研究组的49.3分,p = 0.01)以及术后Harris髋关节评分更高(93.8分对90.6分,p = 0.0003)。研究组有2髋(1.4%)进行了翻修。相比之下,对照组有31髋(5.0%)转为全髋关节置换;31髋中有20髋因股骨部件松动而翻修。髋关节假体的五年生存率在研究组为98.6%,在对照组为93.6%(p = 0.0401)。当根据体重指数是否<25、25至29或≥30将整个队列分为三组时,发现随着体重指数增加,翻修风险从一组到下一组降低了两倍(p = 0.013)。两组均无髋臼部件松动。研究组股骨部件的平均直径为48.3mm,对照组为46.8mm(p = 0.0001)。在体重指数≥35的27例患者亚组中,未因任何原因进行翻修,也未观察到透光线。
金属对金属表面置换髋关节成形术在高体重指数患者中表现良好,尽管与体重指数<30的患者相比功能评分有所降低。高体重指数对生存结果的保护作用可能是由于该患者群体活动水平降低和部件尺寸更大所致。