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金属对金属髋关节表面置换术早期股骨失败的风险因素分析:骨密度和体重指数的影响。

Risk factor analysis for early femoral failure in metal-on-metal hip resurfacing arthroplasty: the effect of bone density and body mass index.

机构信息

Midlands Orthopaedics, p,a, Columbia, SC, USA.

出版信息

J Orthop Surg Res. 2012 Jan 10;7:1. doi: 10.1186/1749-799X-7-1.

Abstract

BACKGROUND

The importance of appropriately selecting patients based on factors such as bone mineral density, body mass index, age, gender, and femoral component size has been demonstrated in many studies as an aid in decreasing the rate of revisions and improving the outcomes for patients after hip resurfacing arthroplasty (HRA); however, there are few published studies quantitatively specifying the potential risk factors that affect early femoral component failures. Therefore, the purpose of this study was to investigate the specific causes of early femoral component failures in hip resurfacing separately and more carefully in order to develop strategies to prevent these failures, rather than excluding groups of patients from this surgical procedure.

METHODS

This retrospective study included 373 metal-on-metal HRAs performed by a single surgeon using the vascular sparing posterior minimally invasive surgical approach. The average length of follow-up was 30 ± 6 months. In order to understand the causes of early femoral failure rate, a multivariable logistic regression model was generated in order to analyze the effects of bone mineral density (T-score), gender, diagnosis, body mass index, femoral implant fixation type, age, and femoral component size.

RESULTS

The average post-operative Harris hip score was 92 ± 11 points and the average post-operative UCLA score was 7 ± 2 points. There were three revisions due to femoral neck fracture and two for femoral component loosening. These occurred in two female and three male patients. In the multi-variable regression model, only T-score and body mass index showed significant effects on the failure rate of femoral components. Patients with a lower T-score and a higher body mass index had a significantly increased risk of early femoral component failure.

CONCLUSION

We recommend that dual energy x-ray absorptiometry scan T-score tests should be routinely performed on all hip resurfacing patients pre-operatively. If a patient has a low T-score (≤ -1.5), consideration should be given to additional precautions or treatments to alleviate his or her risk, especially when the patient has a higher body mass index (≥ 29 kg/m2).

摘要

背景

许多研究已经证明,根据骨密度、体重指数、年龄、性别和股骨部件大小等因素适当选择患者对于降低髋关节表面置换术(HRA)后翻修率和改善患者预后非常重要;然而,很少有发表的研究定量确定影响早期股骨部件失败的潜在危险因素。因此,本研究的目的是更仔细地分别研究髋关节表面置换术早期股骨部件失败的具体原因,以便制定预防这些失败的策略,而不是将患者排除在该手术之外。

方法

本回顾性研究纳入了一位医生采用血管保留后侧微创入路完成的 373 例金属对金属髋关节表面置换术。平均随访时间为 30±6 个月。为了了解早期股骨失败率的原因,我们建立了多变量逻辑回归模型,以分析骨密度(T 评分)、性别、诊断、体重指数、股骨植入物固定类型、年龄和股骨部件大小的影响。

结果

术后平均 Harris 髋关节评分为 92±11 分,UCLA 平均评分为 7±2 分。有 3 例因股骨颈骨折和 2 例因股骨部件松动而进行了翻修。这些发生在 2 名女性和 3 名男性患者中。在多变量回归模型中,只有 T 评分和体重指数对股骨部件的失败率有显著影响。T 评分较低和体重指数较高的患者发生早期股骨部件失败的风险显著增加。

结论

我们建议所有髋关节表面置换术患者术前应常规行双能 X 线吸收仪扫描 T 评分检查。如果患者 T 评分较低(≤-1.5),应考虑采取额外的预防措施或治疗方法来减轻其风险,尤其是当患者体重指数较高(≥29kg/m2)时。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bf3/3284462/8a89608c7f00/1749-799X-7-1-1.jpg

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