Al-Mutairi Nawaf
Department of Dermatology, Farwaniya Hospital, Kuwait.
Med Princ Pract. 2008;17(1):43-8. doi: 10.1159/000109589.
To determine the clinical profile, etiologic factors, disease associations, and the laboratory profile of adult patients with cutaneous leukocytoclastic vasculitis (LV) presenting to the Dermatology Department at Farwaniya Hospital, Kuwait.
The medical records of 57 adult patients (>18 years) with biopsy-proven cutaneous LV from January 2004 to June 2006 at Farwaniya Hospital were reviewed.
Of the 57 patients studied, 21 (36.8%) were classified as having primary cutaneous small vessel vasculitis. The most common type of skin lesions found was palpable purpura seen in 29 (50.9%) patients. No possible cause for the cutaneous vasculitis could be identified in 21 patients. Extracutaneous involvement was seen in 32 (56.1%) patients of which 29 had joint involvement. The most frequent laboratory abnormality was an elevated erythrocyte sedimentation rate (ESR). Altered laboratory evaluation in the form of leukocytosis, raised antistreptolysin O titers and urine abnormalities were found in association with systemic vasculitis. IgA deposits were present in 33 patients. Risk factors for chronicity of cutaneous LV were female sex, advanced age, unidentified etiology, absence of fever and presence of joint involvement.
The commonest type of LV in Kuwait is primary cutaneous small vessel vasculitis. The most frequent laboratory abnormality associated with LV was increased ESR.
确定科威特法瓦尼亚医院皮肤科成年皮肤白细胞破碎性血管炎（LV）患者的临床特征、病因、疾病关联及实验室检查结果。
回顾了2004年1月至2006年6月在法瓦尼亚医院经活检证实为皮肤LV的57例成年患者（>18岁）的病历。
在研究的57例患者中，21例（36.8%）被归类为原发性皮肤小血管炎。最常见的皮肤病变类型是可触及的紫癜，见于29例（50.9%）患者。21例患者未发现皮肤血管炎的可能病因。32例（56.1%）患者有皮肤外受累，其中29例有关节受累。最常见的实验室异常是红细胞沉降率（ESR）升高。发现白细胞增多、抗链球菌溶血素O滴度升高和尿液异常等实验室检查结果改变与系统性血管炎有关。33例患者存在IgA沉积。皮肤LV慢性化的危险因素为女性、高龄、病因不明、无发热及有关节受累。
科威特最常见的LV类型是原发性皮肤小血管炎。与LV相关的最常见实验室异常是ESR升高。
