Poursharif B, Korst L M, Fejzo M S, MacGibbon K W, Romero R, Goodwin T M
Department of Obstetrics and Gynecology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
J Perinatol. 2008 Mar;28(3):176-81. doi: 10.1038/sj.jp.7211906. Epub 2007 Dec 6.
To describe the psychosocial burden of hyperemesis gravidarum (HG) in a large cohort of affected women, focusing on previously unreported problems.
Women with HG described their pregnancy history in an open-ended survey administered internationally through an HG website during 2003 to 2005.
Of the 808 participants, 626 (77.5%) were American. A large majority (82.8%) reported that HG caused negative psychosocial changes, consisting of (1) socioeconomic changes, for example, job loss or difficulties, (2) attitude changes including fear regarding future pregnancies and (3) psychiatric sequelae, for example, feelings of depression and anxiety, which for some continued postpartum. Women who reported that their health-care provider was uncaring or unaware of the severity of their symptoms were nearly twice as likely to report these psychiatric sequelae (odds ratio 1.86, 95% confidence interval 1.06 to 3.29, P=0.032).
Over 80% of a large cohort of women with HG reported that HG caused a negative psychosocial impact.
描述一大群妊娠剧吐（HG）女性的心理社会负担，重点关注此前未报告的问题。
患有HG的女性在2003年至2005年期间通过一个HG网站在国际范围内进行的一项开放式调查中描述了她们的怀孕史。
在808名参与者中，626名（77.5%）是美国人。绝大多数（82.8%）报告称HG导致了负面的心理社会变化，包括：（1）社会经济变化，例如失业或困难；（2）态度变化，包括对未来怀孕的恐惧；（3）精神后遗症，例如抑郁和焦虑情绪，其中一些在产后仍持续存在。报告称其医疗服务提供者冷漠或未意识到其症状严重性的女性报告这些精神后遗症的可能性几乎是其他人的两倍（优势比1.86，95%置信区间1.06至3.29，P = 0.032）。
一大群患有HG的女性中，超过80%报告称HG造成了负面的心理社会影响。
