Paul Geo, Steuernagel Stefan, Koller Hubert
Institut für Physikalische Chemie and Graduate School of Chemistry, Westfälische Wilhelms-Universität, Corrensstrasse 36, Münster, Germany.
Chem Commun (Camb). 2007 Dec 28(48):5194-6. doi: 10.1039/b711105c. Epub 2007 Oct 17.
The drug molecule Propranolol has been encapsulated by a sol-gel process in an organic-inorganic hybrid matrix by in-situ self-assembly; the 2D HETCOR solid state NMR spectroscopy provides direct proof of the intimate spatial relationship between the host matrix and guest drug molecules.
药物分子普萘洛尔已通过溶胶-凝胶法原位自组装封装在有机-无机杂化基质中;二维异核化学位移相关固体核磁共振光谱直接证明了主体基质与客体药物分子之间紧密的空间关系。