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源自非动物的透明质酸：一种结构和化学特征与透明质酸相当的新来源。

Non-Animal Hyaluronic Acid from : A New Source with a Structure and Chemical Profile Comparable to Hyaluronic Acid.

作者信息

Galla Rebecca, Mulè Simone, Ferrari Sara, Parini Francesca, Givonetti Annalisa, Cavaletto Maria, Miletto Ivana, Paul Geo, Giovenzana Giovanni Battista, Marchese Leonardo, Molinari Claudio, Uberti Francesca

机构信息

Noivita S.r.l.s., Spin Off of University of Piemonte Orientale, Via Solaroli 17, 28100 Novara, Italy.

Department for Sustainable Development and Ecological Transition, University of Piemonte Orientale, Piazza Sant'Eusebio 5, 13100 Vercelli, Italy.

出版信息

Foods. 2025 Apr 15;14(8):1362. doi: 10.3390/foods14081362.

DOI:10.3390/foods14081362
PMID:40282763
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12027390/
Abstract

is high in polysaccharides, which have a structure made up of a straight chain of (1→3) α-D-mannan and side chains of glucuronic acid, xylose, and fucose. This study aimed to evaluate whether the non-animal hyaluronic acid extracted from can maintain the chemical and physical characteristics of hyaluronic acid that ensure its biological functionality. Chemical and physical analyses such as hyaluronic content, screening of metals, purity, pH, nuclear magnetic resonance (NMR), Fourier transform infrared spectroscopy (ATR/FTIR), and MALDI-TOF were performed. Chemical characterisation revealed that the most abundant polysaccharide in the extract was hyaluronic acid, accounting for ca. 87.76%, with a molecular weight above 2000 kDa. In addition, ATR/FTIR and NMR spectroscopy and MALDI-TOF analysis confirmed that extract is a source of non-animal hyaluronic acid. In summary, every molecular attribute examined played a significant role in determining the functional qualities of the extract, indicating that a thoughtful choice of extraction technique can enhance its advantages.

摘要

富含多糖，其结构由(1→3)α-D-甘露聚糖直链以及葡萄糖醛酸、木糖和岩藻糖侧链组成。本研究旨在评估从[具体来源未给出]中提取的非动物透明质酸是否能保持透明质酸的化学和物理特性，这些特性确保了其生物学功能。进行了诸如透明质酸含量、金属筛选、纯度、pH值、核磁共振(NMR)、傅里叶变换红外光谱(ATR/FTIR)和基质辅助激光解吸电离飞行时间质谱(MALDI-TOF)等化学和物理分析。化学表征显示提取物中最丰富的多糖是透明质酸，约占87.76%，分子量超过2000 kDa。此外，ATR/FTIR和NMR光谱以及MALDI-TOF分析证实[具体提取物未明确]提取物是非动物透明质酸的来源。总之，所检测的每个分子属性在确定提取物的功能特性方面都发挥了重要作用，表明精心选择提取技术可以增强其优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d641/12027390/7d4a76f984d3/foods-14-01362-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d641/12027390/34273dee4087/foods-14-01362-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d641/12027390/438ef095eed6/foods-14-01362-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d641/12027390/38c99303b226/foods-14-01362-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d641/12027390/4bd484ada2c0/foods-14-01362-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d641/12027390/e18b79de6e38/foods-14-01362-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d641/12027390/7d4a76f984d3/foods-14-01362-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d641/12027390/34273dee4087/foods-14-01362-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d641/12027390/438ef095eed6/foods-14-01362-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d641/12027390/38c99303b226/foods-14-01362-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d641/12027390/4bd484ada2c0/foods-14-01362-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d641/12027390/e18b79de6e38/foods-14-01362-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d641/12027390/7d4a76f984d3/foods-14-01362-g006.jpg

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Tremella fuciformis beverage improves glycated hemoglobin A1c and waist circumference in overweight/obese prediabetic subjects: a randomized controlled trial.
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