使用异体真皮移植的阴道旁修补术：长期疗效
Vaginal paravaginal repair with an AlloDerm graft: Long-term outcomes.
作者信息
Ward Renée M, Sung Vivian W, Clemons Jeffrey L, Myers Deborah L
机构信息
Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, Warren Alpert Medical School of Brown University, Providence, RI, USA.
出版信息
Am J Obstet Gynecol. 2007 Dec;197(6):670.e1-5. doi: 10.1016/j.ajog.2007.08.067.
OBJECTIVE
The aim of this study was to describe the long-term objective and subjective outcomes after vaginal paravaginal repair with AlloDerm graft (LifeCell, Branchburg, NJ).
STUDY DESIGN
Thirty-three women with either recurrent stage II or primary or recurrent stage III-IV anterior vaginal wall prolapse underwent a vaginal paravaginal repair with AlloDerm graft between November 1998 and April 2002. Postoperative follow-up was obtained on an annual basis. Objective failure was defined as a stage II or greater anterior wall defect. Descriptive statistics were performed.
RESULTS
Long-term follow-up was obtained on 24/33 subjects (72.7%). The mean length of follow-up for the 24 women was 52.0 months (range, 18-86 months). Fourteen of the 24 subjects (58.3%) had recurrent stage II prolapse in the anterior compartment, of which only 4 of 14 (28.6%) were symptomatic.
CONCLUSIONS
Long-term evaluation of vaginal paravaginal repairs with AlloDerm graft reveals good subjective success, despite a moderate rate of objective failure within the first 24 months.
目的
本研究旨在描述使用异体真皮移植物（LifeCell公司，新泽西州布兰奇堡）进行阴道旁修补术后的长期客观和主观结果。
研究设计
1998年11月至2002年4月期间，33例患有复发性II期或原发性或复发性III-IV期阴道前壁脱垂的女性接受了使用异体真皮移植物的阴道旁修补术。每年进行术后随访。客观失败定义为II期或更严重的前壁缺损。进行描述性统计。
结果
对33名受试者中的24名（72.7%）进行了长期随访。这24名女性的平均随访时间为52.0个月（范围为18-86个月）。24名受试者中有14名（58.3%）在前间隔出现复发性II期脱垂，其中14名中有4名（28.6%）有症状。
结论
对使用异体真皮移植物进行阴道旁修补术的长期评估显示，尽管在最初24个月内客观失败率适中，但主观成功率良好。
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