Straumann Alex
Department of Gastroenterology, Kantonsspital Olten, Roemerstrasse 7, 4600 Olten, Switzerland.
Gastrointest Endosc Clin N Am. 2008 Jan;18(1):99-118; ix. doi: 10.1016/j.giec.2007.09.009.
Eosinophilic esophagitis is a chronic disease limited to the esophagus and has a persistent or spontaneously fluctuating course. So far it does not seem to limit life expectancy, but it often substantially impairs the quality of life. To date, there has been no association with malignant conditions, but there is concern that the chronic, uncontrolled inflammation will evoke irreversible structural alterations of the esophagus, leading to tissue fibrosis, stricture formation, and impaired function. This esophageal remodeling may result in several disease-inherent and procedure-related complications.
嗜酸性食管炎是一种局限于食管的慢性疾病，病程持续或自发波动。迄今为止，它似乎并不影响预期寿命，但常常严重损害生活质量。到目前为止，尚未发现它与恶性疾病有关，但人们担心慢性、未得到控制的炎症会引起食管不可逆的结构改变，导致组织纤维化、狭窄形成及功能受损。这种食管重塑可能会引发一些疾病本身及与治疗相关的并发症。
