Neale Donna M, Cootauco Alice Chung, Burrow Gerard
Department of Gynecology and Obstetrics, Division of Maternal-Fetal Medicine, Johns Hopkins Hospital, 600 N. Wolfe Street, Phipps 228, Baltimore, MD 21287-1228, USA.
Clin Perinatol. 2007 Dec;34(4):543-57, v-vi. doi: 10.1016/j.clp.2007.10.003.
Twenty-seven million Americans are affected with thyroid disease, yet over half of this population remains undiagnosed. Thyroid disease often manifests itself during the reproductive period of a woman's life and is the second most common endocrinopathy that affects women of childbearing age. The physiologic changes of pregnancy can mimic thyroid disease or cause a true remission or exacerbation of underlying disease. In addition, thyroid hormones are key players in fetal brain development. Maternal, fetal and neonatal thyroid are discussed here. Moreover, this article serves as a review of the more common thyroid diseases that are encountered during pregnancy and the postnatal period, their treatments, and their potential effects on pregnancy.
2700万美国人患有甲状腺疾病，但其中超过一半的人仍未得到诊断。甲状腺疾病通常在女性的生育期出现，是影响育龄女性的第二常见内分泌疾病。怀孕时的生理变化可能会模仿甲状腺疾病，或导致潜在疾病真正缓解或加重。此外，甲状腺激素是胎儿大脑发育的关键因素。本文将讨论母体、胎儿和新生儿的甲状腺情况。此外，本文还将对孕期和产后更常见的甲状腺疾病、其治疗方法及其对妊娠的潜在影响进行综述。
