Velagaleti Raghava S, Vasan Ramachandran S
Framingham Heart Study, Framingham, MA 01702-5803, USA.
Cardiol Clin. 2007 Nov;25(4):487-95; v. doi: 10.1016/j.ccl.2007.08.010.
Hypertension and coronary disease are major risk factors for the incidence and progression of heart failure. These two risk factors frequently coexist, and have additive and synergistic effects that promote both left ventricular remodeling and heart failure in the general population. The relative contributions of these two risk factors to heart failure burden in the community may vary based on age, gender, and race. In general, attribution of heart failure in the community to solely one of these two risk factors is inappropriate. Prevention of both hypertension and coronary disease is important for preventing heart failure in the twenty-first century.
高血压和冠状动脉疾病是心力衰竭发生和进展的主要危险因素。这两种危险因素经常并存，并具有累加和协同效应，可促进普通人群的左心室重塑和心力衰竭。这两种危险因素对社区心力衰竭负担的相对贡献可能因年龄、性别和种族而异。一般来说，将社区中的心力衰竭单纯归因于这两种危险因素中的某一种是不合适的。在21世纪，预防高血压和冠状动脉疾病对于预防心力衰竭都很重要。
