Mnescu Rodica, Niculescu Mihaela, Barascu Doina, Mocanu Carmen, Mîndril I
Catedra de anatomie, UMF Craiova.
Oftalmologia. 2007;51(3):91-4.
The authors have suggested to reveal conjunctiva stamp changes in diabetic patients. A set of patients aged between 50 - 80 and having been diagnosed with diabetes mellitus were available for our study, therefore they have been ophthalmologically examined; both Schrimer and BUT tests have been performed. We removed conjunctiva stamps which, after being fixed and Giemsa stained, they were investigated by photonic microscopy. As to compare them we removed conjunctiva stamps from a group of control which was also Schrimer and BUT tested.
Both Schrimer and BUT tests pleaded for lacrimal hyposecretion in most of the diabetic patients; their conjunctiva stamps presented changes at the levels of both epithelial and calyciforme cells. Conjunctiva stamps were significantly changed in the old patients with a long lasted diabetes evolution pleading for the diagnosis of lacrimal hyposecretion syndrome (dry eye syndrome) in those patients.
作者建议揭示糖尿病患者结膜印记的变化。我们的研究纳入了一组年龄在50至80岁之间且已被诊断为糖尿病的患者，因此对他们进行了眼科检查；同时进行了泪液分泌试验（Schrimer试验）和泪膜破裂时间（BUT）检测。我们取下结膜印记，在固定并进行吉姆萨染色后，通过光子显微镜进行观察。为了进行比较，我们从一组同样进行了Schrimer试验和BUT检测的对照组中取下结膜印记。
在大多数糖尿病患者中，Schrimer试验和BUT检测均提示泪液分泌不足；他们的结膜印记在上皮细胞和杯状细胞水平均出现了变化。在糖尿病病程较长的老年患者中，结膜印记有显著改变，这支持了这些患者泪液分泌不足综合征（干眼综合征）的诊断。
