Vetter Ch, Bonél H, Robert-Tissot L, Bielecki W J
Klinik und Poliklinik für Allgemeine Innere Medizin.
Praxis (Bern 1994). 2007 Nov 14;96(46):1815-20. doi: 10.1024/1661-8157.96.46.1815.
Pneumatosis cystoides intestinalis (PCI) is a rare illness in adults with gas filled blebs found in the submucosa or subserosa of the bowel wall. The main localization is the terminal ileum although all parts of the intestine can be affected. Clinical symptoms can vary from aqueous-slimy, bloody diarrhea to constipation and/or vague abdominal pain. Patients can also be completely asymptomatic. In symptomatic patients the therapy of PI is based on the assumed pathogenesis, so that a combined treatment of metronidazole 1500 mg daily during a period of 6-8 weeks additionally and oxygen application (PaO2 of 200-350 mmHg) for 7 days is suggested. In addition, elemental diets are recommended. Complications are indicated in the literature with 3%. In particular mechanical ileus, invagination and perforation as well as substantial intestinal bleeding up to the volvolus lead to further diagnostic and therapeutic steps. A surgical intervention is reserved for rare cases.
肠气囊肿病(PCI)是一种在成人中罕见的疾病,在肠壁黏膜下层或浆膜下层发现充满气体的小泡。主要发病部位是回肠末端,不过肠道的所有部位都可能受到影响。临床症状从水样黏液便、血性腹泻到便秘和/或腹部隐痛不等。患者也可能完全没有症状。对于有症状的患者,PCI的治疗基于假定的发病机制,因此建议在6 - 8周内每天额外联合使用1500毫克甲硝唑,并进行7天的吸氧治疗(动脉血氧分压为200 - 350毫米汞柱)。此外,推荐使用要素饮食。文献表明并发症发生率为3%。特别是机械性肠梗阻、肠套叠和穿孔以及直至肠扭转的大量肠道出血,都需要进一步的诊断和治疗措施。手术干预仅适用于罕见病例。